Title:
COMPOSITION FOR IMPROVING NEURITE OUTGROWTH
Document Type and Number:
WIPO Patent Application WO/2021/149806
Kind Code:
A1
Abstract:
A composition usable for a specific use, such as a composition for improving neurite outgrowth is provided. Such a composition is provided by using indole-3-lactic acid (ILA) or an indole-3-lactic acid-producing bacterium is used as an active ingredient.
Inventors:
WONG CHYN BOON (JP)
KUHARA TETSUYA (JP)
KUHARA TETSUYA (JP)
Application Number:
PCT/JP2021/002271
Publication Date:
July 29, 2021
Filing Date:
January 22, 2021
Export Citation:
Assignee:
MORINAGA MILK INDUSTRY CO LTD (JP)
International Classes:
A23L33/10; A23L33/135; A61K31/404; A61K35/745; A61P25/00; A61P25/28
Domestic Patent References:
| WO2003094914A1 | 2003-11-20 | |||
| WO2017130859A1 | 2017-08-03 | |||
| WO2013144077A1 | 2013-10-03 |
Foreign References:
| US20190083549A1 | 2019-03-21 | |||
| US20190134114A1 | 2019-05-09 | |||
| JP2016003187A | 2016-01-12 | |||
| KR20110057550A | 2011-06-01 |
Other References:
HAN QIAN, ROBINSON HOWARD, CAI TAO, TAGLE DANILO A., LI JIANYONG: "Structural Insight into the Inhibition of Human Kynurenine Aminotransferase I/Glutamine Transaminase K", JOURNAL OF MEDICINAL CHEMISTRY, AMERICAN CHEMICAL SOCIETY, vol. 52, no. 9, 14 May 2009 (2009-05-14), pages 2786 - 2793, XP055831437, ISSN: 0022-2623, DOI: 10.1021/jm9000874
WONG CHYN BOON, AZUSA TANAKA, TETSUYA KUHARA, JIN-ZHONG XIAO: "Potential effects of indole-3-lactic acid, a metabolite of human bifidobacteria, on NGF-induced neurite outgrowth in PC12 cells", MICROORGANISMS, vol. 8, no. 3, 12 March 2020 (2020-03-12), XP055831439, DOI: 10.3390/microorganisms8030398
Y J CHYAN, B POEGGELER, R A OMAR, D G CHAIN, B FRANGIONE, J GHISO, M A PAPPOLLA: "Potent neuroprotective properties against the Alzheimer beta-amyloid by an endogenous melatonin-related indole structure, indole-3-propionic acid", THE JOURNAL OF BIOLOGICAL CHEMISTRY, UNITED STATES, 30 July 1999 (1999-07-30), UNITED STATES, pages 21937, XP055221599, Retrieved from the Internet
WONG CHYN BOON, AZUSA TANAKA, TETSUYA KUHARA, JIN-ZHONG XIAO: "Potential effects of indole-3-lactic acid, a metabolite of human bifidobacteria, on NGF-induced neurite outgrowth in PC12 cells", MICROORGANISMS, vol. 8, no. 3, 12 March 2020 (2020-03-12), XP055831439, DOI: 10.3390/microorganisms8030398
Y J CHYAN, B POEGGELER, R A OMAR, D G CHAIN, B FRANGIONE, J GHISO, M A PAPPOLLA: "Potent neuroprotective properties against the Alzheimer beta-amyloid by an endogenous melatonin-related indole structure, indole-3-propionic acid", THE JOURNAL OF BIOLOGICAL CHEMISTRY, UNITED STATES, 30 July 1999 (1999-07-30), UNITED STATES, pages 21937, XP055221599, Retrieved from the Internet
Attorney, Agent or Firm:
IP FIRM SHUWA (JP)
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