Title:
COMPOSITION INCLUDING PEPTIDE COMPOUND AND SURFACTANT
Document Type and Number:
WIPO Patent Application WO/2023/063376
Kind Code:
A1
Abstract:
The present invention relates to a composition including components (1) and (2). (1) A peptide compound that is at least one selected from the group consisting of (i), (ii), and (iii): (i) a peptide compound containing one or a plurality of N-substituted amino acid residues; (ii) a peptide compound having a ClogP of 4-25; and (iii) a peptide compound having a solubility of 10 mg/mL or less in a 50 mM phosphate buffer solution (pH 6.5) at 37°C and 1 atm. (2) A surfactant that is at least one selected from the group consisting of (iv) and (v): (iv) a surfactant having a straight-chain alkylene structure, the alkylene structure having 5-13 carbon atoms; and (v) a surfactant having a carnitine residue.
Inventors:
NAKAE SHINICHI (JP)
TAKANO RYUSUKE (JP)
TANG HENGMIN (JP)
SAKURAI YUJI (JP)
TAKANO RYUSUKE (JP)
TANG HENGMIN (JP)
SAKURAI YUJI (JP)
Application Number:
PCT/JP2022/038128
Publication Date:
April 20, 2023
Filing Date:
October 12, 2022
Export Citation:
Assignee:
CHUGAI PHARMACEUTICAL CO LTD (JP)
International Classes:
A61K38/12; A61K9/08; A61K38/00; A61K47/12; A61K47/14; A61K47/18; A61K47/20; A61K47/44
Domestic Patent References:
| WO2021090855A1 | 2021-05-14 | |||
| WO2018225864A1 | 2018-12-13 | |||
| WO2018225851A1 | 2018-12-13 |
Foreign References:
| JP2014518213A | 2014-07-28 | |||
| JP2015529684A | 2015-10-08 | |||
| JP2009518437A | 2009-05-07 |
Other References:
TSUCHIYA, AKEMI ET AL.: "Can a tacrolimus-cyclosporin injection be administered accurately? - Examination of errors when administering using an infusion pump.", TRANSPLANTATION NOW, NIHON IGAKUKAN, JP, vol. 13, no. 2, 1 January 2000 (2000-01-01), JP , pages 173 - 175, XP009545422, ISSN: 0916-0094
Attorney, Agent or Firm:
HASEGAWA Yoshiki et al. (JP)
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