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Title:
COMPOSITION FOR INCREASING AMOUNT OF FOOD INGESTED AND/OR IMPROVING ANOREXIA, AND COMPOSITION FOR ACTIVATING TRANSIENT RECEPTOR POTENTIAL ANKYRIN 1
Document Type and Number:
WIPO Patent Application WO/2023/090313
Kind Code:
A1
Abstract:
The purpose of the present invention is to newly discover a transient receptor potential ankyrin 1 (TRPA1) agonist that exhibits an action for increasing the amount of food ingested, to provide a novel agonist of TRPA1, or to provide a novel active ingredient that exhibits an action for increasing the amount of food ingested or an action for improving anorexia. A compound having a specific fatty acid or a specific anthraquinone structure has an effect for activating TRPA1 and can be used as an active ingredient for increasing the amount of food ingested and/or improving anorexia.

Inventors:
IWASAKI YUSAKU (JP)
Application Number:
PCT/JP2022/042367
Publication Date:
May 25, 2023
Filing Date:
November 15, 2022
Export Citation:
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Assignee:
KYOTO PREFECTURAL PUBLIC UNIV CORP (JP)
International Classes:
A23L33/10; A23L33/105; A23L33/12; A61K31/122; A61K31/192; A61K31/201; A61P1/14; A61P25/02; A61P43/00; C07C50/16; C07C66/02
Domestic Patent References:
WO2017081296A12017-05-18
Foreign References:
JP2010519311A2010-06-03
US20070248586A12007-10-25
JP2020504118A2020-02-06
JPH10130201A1998-05-19
JP2014076979A2014-05-01
JP2020109065A2020-07-16
Other References:
S BANG; S YOO; TJ YANG; H CHO; YG KIM; SW HWANG: "Resolvin D1 attenuates activation of sensory transient receptor potential channels leading to multiple anti‐nociception", BRITISH JOURNAL OF PHARMACOLOGY, WILEY-BLACKWELL, UK, vol. 161, no. 3, 2 June 2010 (2010-06-02), UK , pages 707 - 720, XP071171206, ISSN: 0007-1188, DOI: 10.1111/j.1476-5381.2010.00909.x
Attorney, Agent or Firm:
TANAKA Shinichiro et al. (JP)
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