Title:
COMPOSITION FOR INNATE IMMUNITY ENHANCEMENT AND ANTIVIRAL ACTIVITY CONTAINING HOVENIA DULCIS EXTRACT AS ACTIVE INGREDIENT
Document Type and Number:
WIPO Patent Application WO/2016/159583
Kind Code:
A3
Abstract:
The present invention relates to a pharmaceutical composition for innate immunity enhancement and antiviral activity containing a Hovenia dulcis extract as an active ingredient, a health functional food for innate immunity enhancement and antiviral activity containing a Hovenia dulcis extract as an active ingredient, a feed composition for innate immunity enhancement and antiviral activity containing a Hovenia dulcis extract as an active ingredient, and a method for innate immunity enhancement and antiviral activity enhancement in an animal, the method comprising administering a Hovenia dulcis extract to an animal excluding humans, in need of innate immunity enhancement. The Hovenia dulcis-containing composition for innate immunity enhancement and antiviral activity according to the present invention exhibits antiviral activity and innate immunity enhancement efficacy, and thus can be applied for prevention and treatment of bacterial and viral infectious diseases, and can be widely used for a medicine or a health functional food for immunity enhancement and regulation in immunodeficient or immunosuppressed patients and for a feed for innate immunity enhancement and antiviral activity, for the purpose of anti-disease enhancement of animals. Furthermore, the composition for innate immunity enhancement and antiviral activity according to the present invention scarcely causes toxicity or side effects, and thus can be safely used even in the long-term use for prophylactic purposes.
Inventors:
MA JIN YEUL (KR)
CHO WON-KYUNG (KR)
LEE JONG-SOO (KR)
CHO WON-KYUNG (KR)
LEE JONG-SOO (KR)
Application Number:
PCT/KR2016/003043
Publication Date:
December 08, 2016
Filing Date:
March 25, 2016
Export Citation:
Assignee:
KOREA INST ORIENTAL MEDICINE (KR)
International Classes:
A61K36/72; A61K9/20; A61K9/48
Foreign References:
| KR20060099225A | 2006-09-19 |
Other References:
WANG, M. ET AL.: "Preparation, Preliminary Characterization and Immunostimulatory Activity of Polysaccharide Fractions from the Peduncles of Hovenia Dulcis.", FOOD CHEMISTRY, vol. 138, 2013, pages 41 - 47, XP055332350
KIM, H. -L. ET AL.: "The AMPK Pathway Mediates an Anti-adipogenic Effect of Fruits of Hovenia Dulcis Thunb.", FOOD & FUNCTION, vol. 5, 2014, pages 2961 - 2968, XP055332353
LEE, J. J. ET AL.: "Liver Fibrosis Protective Effect of Hovenia Dulcis Fruit.", CURRENT TOPICS IN NUTRACEUTICALS RESEARCH, vol. 12, no. 1/2, 2014, pages 43 - 50, XP055332354
FANG, H. -L. ET AL.: "Treatment of Chronic Liver Injuries in Mice by Oral Administration of Ethanolic Extract of the Fruit of Hovenia Dulcis.", THE AMERICAN JOURNAL OF CHINESE MEDICINE, vol. 35, no. 4, 2007, pages 693 - 703
KIM, H. -L. ET AL.: "The AMPK Pathway Mediates an Anti-adipogenic Effect of Fruits of Hovenia Dulcis Thunb.", FOOD & FUNCTION, vol. 5, 2014, pages 2961 - 2968, XP055332353
LEE, J. J. ET AL.: "Liver Fibrosis Protective Effect of Hovenia Dulcis Fruit.", CURRENT TOPICS IN NUTRACEUTICALS RESEARCH, vol. 12, no. 1/2, 2014, pages 43 - 50, XP055332354
FANG, H. -L. ET AL.: "Treatment of Chronic Liver Injuries in Mice by Oral Administration of Ethanolic Extract of the Fruit of Hovenia Dulcis.", THE AMERICAN JOURNAL OF CHINESE MEDICINE, vol. 35, no. 4, 2007, pages 693 - 703
Attorney, Agent or Firm:
CHOI, Kyu Whan (12th floor 745, Hanbat-daero,Seo-gu, Daejeon, KR)
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