COMPOSITION AND METHOD FOR TREATING NONALCOHOLIC STEATOHEPATITIS

WIPO Patent Application WO1999029330

A8

Nonalcoholic steatohepatitis (NASH) is a disease of the liver characterized by inflammation and damage to the liver cells. Typically, steatohepatitis involves inflammation of the liver related to fat accumulation, and mimics alcoholic hepatitis but is observed in patients who seldom or never consume alcohol. Nonalcoholic steatohepatitis can lead to serious liver damage, and ultimately cirrhosis. The present invention provides methods and compositions useful for the treatment or alleviation of nonalcoholic steatohepatitis and the pharmaceutical formulations for their administration to a human. Specifically, compositions comprised of lecithin, antioxidants and vitamin B complex are administered parenterally, most preferably by oral administration. Specific therapeutic formulations include admixtures of these compounds and specific dosage formulations include daily oral administrations of these compounds in tablet or powder forms.

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FAN DAVID
HSIA HOUN SIMON

PCT/US1998/025701

September 10, 1999

December 04, 1998

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VIVA AMERICA MARKETING INC (US)

A61K33/04; (IPC1-7): A61K33/04; A61K31/34; A61K31/355; A61K31/685

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