Title:
COMPOSITION FOR ORAL USE
Document Type and Number:
WIPO Patent Application WO/2012/039101
Kind Code:
A1
Abstract:
In the conventional caries prevention methods using antibacterial agents, enzyme inhibitors or antibiotics, extracellular polysaccharides of oral biofilms inhibit the penetration of the antibacterial agents, enzyme inhibitors, antibiotics or the like and, therefore, desired anticarious effects can be hardly achieved. In addition, it is not preferred to use such antibacterial agents and the like because of the high risk of inducing the appearance of resistant bacteria. Accordingly, it has been required to develop a more safe and more effective method for preventing caries not by controlling caries causing bacteria but by preventing biofilm formation by the caries causing bacteria. The present invention enables the prevention of biofilm formation leading to dental caries by using a composition which regulates quorum sensing.
Inventors:
TSUGANE TAKANORI (JP)
SAEKI YOJI (JP)
SAEKI YOJI (JP)
Application Number:
PCT/JP2011/005002
Publication Date:
March 29, 2012
Filing Date:
September 07, 2011
Export Citation:
Assignee:
LOTTE CO LTD (JP)
TSUGANE TAKANORI (JP)
SAEKI YOJI (JP)
TSUGANE TAKANORI (JP)
SAEKI YOJI (JP)
International Classes:
A23G4/00; A61K45/00; A23L1/30; A61K8/97; A61K36/48; A61P1/02; A61P31/04; A61Q11/00
Domestic Patent References:
| WO2010050369A1 | 2010-05-06 |
Foreign References:
| JP2009269912A | 2009-11-19 | |||
| JPH0881384A | 1996-03-26 | |||
| US4217341A | 1980-08-12 | |||
| JP2010211023A | 2010-09-21 |
Other References:
TEIXEIRA, E.H. ET AL.: "In vitro inhibition of Streptococci binding to enamel acquired pellicle by plant lectins", JOURNAL OF APPLIED MICROBIOLOGY, vol. 101, no. 1, July 2006 (2006-07-01), pages 111 - 116, XP055098531
ANTONIO, A.G. ET AL.: "Species, roasting degree and decaffeination influence the antibacterial activity of coffee against Streptococcus mutans", FOOD CHEMISTRY, vol. 118, no. 3, 1 February 2010 (2010-02-01), pages 782 - 788, XP026563903
HONRAET, K. ET AL.: "Use of the modified robbins device and fluorescent staining to screen plant extracts for the inhibition of S. mutans biofilm formation", JOURNAL OF MICROBIOLOGICAL METHODS, vol. 64, no. 2, February 2006 (2006-02-01), pages 217 - 224, XP027926832
ORAL MICROBIOLOGY AND IMMUNOLOGY, vol. 24, no. 2, 2009, pages 152 - 61
See also references of EP 2620160A4
ANTONIO, A.G. ET AL.: "Species, roasting degree and decaffeination influence the antibacterial activity of coffee against Streptococcus mutans", FOOD CHEMISTRY, vol. 118, no. 3, 1 February 2010 (2010-02-01), pages 782 - 788, XP026563903
HONRAET, K. ET AL.: "Use of the modified robbins device and fluorescent staining to screen plant extracts for the inhibition of S. mutans biofilm formation", JOURNAL OF MICROBIOLOGICAL METHODS, vol. 64, no. 2, February 2006 (2006-02-01), pages 217 - 224, XP027926832
ORAL MICROBIOLOGY AND IMMUNOLOGY, vol. 24, no. 2, 2009, pages 152 - 61
See also references of EP 2620160A4
Attorney, Agent or Firm:
OKABE, Yuzuru et al. (JP)
Okabe 讓 (JP)
Okabe 讓 (JP)
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