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Title:
COMPOSITION FOR PREVENTING, ALLEVIATING, OR TREATING ALZHEIMER'S DISEASE
Document Type and Number:
WIPO Patent Application WO/2023/219227
Kind Code:
A1
Abstract:
The administration of a composition of the present invention can suppress the accumulation of amyloid beta, leading to effective prevention, alleviation, or treatment of amyloidopathies, such as Alzheimer's disease.

Inventors:
LEE HERN KU (KR)
LIM JAE-YOUNG (KR)
Application Number:
PCT/KR2023/001336
Publication Date:
November 16, 2023
Filing Date:
January 30, 2023
Export Citation:
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Assignee:
MICROX CO LTD (KR)
International Classes:
A61K31/198; A23L33/10; A61P25/28
Foreign References:
KR20210065684A2021-06-04
Other References:
KUMAR ASHWANI, JAIN SANDEEP: "Ionotropic Glutamate Receptor Subtype 6: Docking and Site Moiety Map Analysis Study", DER PHARMA CHEMICA, SCHOLARS RESEARCH LIBRARY, INDIA, vol. 4, no. 2, 1 January 2012 (2012-01-01), India , pages 679 - 686, XP093107222, ISSN: 0975-413X
KWO-ON-YUEN, P.F. ; NEWMARK, R.D. ; BUDINGER, T.F. ; KAYE, J.A. ; BALL, M.J. ; JAGUST, W.J.: "BrainN-acetyl-l-aspartic acid in Alzheimer's disease: a proton magnetic resonance spectroscopy study", BRAIN RESEARCH, ELSEVIER, AMSTERDAM, NL, vol. 667, no. 2, 26 December 1994 (1994-12-26), NL , pages 167 - 174, XP027255274, ISSN: 0006-8993
KILLINGSWORTH JESSICA, SAWMILLER DARRELL, SHYTLE R. DOUGLAS: "Propionate and Alzheimer’s Disease", FRONTIERS IN AGING NEUROSCIENCE, FRONTIERS RESEARCH FOUNDATION, CH, vol. 12, 11 January 2021 (2021-01-11), CH , pages 580001, XP093107223, ISSN: 1663-4365, DOI: 10.3389/fnagi.2020.580001
JIMÉNEZ-ESPINOZA CARMEN, MARCANO SERRANO FRANCISCO, GONZÁLEZ-MORA JOSÉ LUIS: "N-Acetylaspartyl-Glutamate Metabolism in the Cingulated Cortices as a Biomarker of the Etiology in ASD: A 1H-MRS Model", MOLECULES, MDPI AG, CH, vol. 26, no. 3, 28 January 2021 (2021-01-28), CH , pages 675, XP093107224, ISSN: 1420-3049, DOI: 10.3390/molecules26030675
Attorney, Agent or Firm:
KIM, Byeong-Pil et al. (KR)
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