Title:
COMPOSITION FOR PREVENTING, ALLEVIATING, OR TREATING LIVER DAMAGE
Document Type and Number:
WIPO Patent Application WO/2018/048274
Kind Code:
A1
Abstract:
The present invention relates to a pharmaceutical composition comprising nutria-derived bile as an active ingredient for the prevention or treatment of liver disease, to a method for the prevention or treatment of liver disease, and to a food composition comprising nutria-derived bile as an active ingredient for the protection of liver or the prevention or alleviation of liver disease. According to the present invention, the composition can be utilized as a substitute product for bear gallbladder by comprising nutria bile as an active ingredient, and thus can be used for improving liver function, suppressing liver damage, and preventing and treating liver disease without side effects.
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Inventors:
YEON SEONG CHAN (KR)
LEE HU JANG (KR)
HONG IL HWA (KR)
LEE SEONG GYU (KR)
HONG SEONG JIN (KR)
JU GI HOE (KR)
LEE HU JANG (KR)
HONG IL HWA (KR)
LEE SEONG GYU (KR)
HONG SEONG JIN (KR)
JU GI HOE (KR)
Application Number:
PCT/KR2017/009953
Publication Date:
March 15, 2018
Filing Date:
September 11, 2017
Export Citation:
Assignee:
NAT UNIV GYEONGSANG IACF (KR)
NAKDONG RIVER BASIN ENV OFFICE (KR)
NAKDONG RIVER BASIN ENV OFFICE (KR)
International Classes:
A61K35/413; A23L33/10
Foreign References:
| KR20080012258A | 2008-02-11 | |||
| KR20050103185A | 2005-10-27 |
Other References:
TRAUNER, M.: "Review article: mechanisms of action and therapeutic applications of ursodeoxycholic acid in chronic liver diseases", ALIMENTARY PHARMACOLOGY & THERAPEUTICS, vol. 13, no. 8, 1999, pages 979 - 996, XP002662995, DOI: 10.1046/j.1365-2036.1999.00596.x
TINT, G. S.: "Ursodeoxycholic acid, 7-ketolithocholic acid, and chenodeoxycholic acid are primary bile acids of the nutria (Myocastor coypus", GASTROENTEROLOGY, vol. 90, no. 3, 1986, pages 702 - 709
SAKSENA, S. ET AL.: "Ursodeoxycholic acid in the treatment of liver diseases", POSTGRADUATE MEDICAL JOURNAL, vol. 73, no. 856, 1997, pages 75 - 80, XP055603858, DOI: 10.1136/pgmj.73.856.75
TINT, G. S.: "Ursodeoxycholic acid, 7-ketolithocholic acid, and chenodeoxycholic acid are primary bile acids of the nutria (Myocastor coypus", GASTROENTEROLOGY, vol. 90, no. 3, 1986, pages 702 - 709
SAKSENA, S. ET AL.: "Ursodeoxycholic acid in the treatment of liver diseases", POSTGRADUATE MEDICAL JOURNAL, vol. 73, no. 856, 1997, pages 75 - 80, XP055603858, DOI: 10.1136/pgmj.73.856.75
Attorney, Agent or Firm:
KIM, Soon Woong (KR)
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