Title:
COMPOSITION FOR PREVENTING OR TREATING ANTICANCER AGENT-INDUCED ALLODYNIA AND THERAPEUTIC METHOD USING SAME
Document Type and Number:
WIPO Patent Application WO/2021/141465
Kind Code:
A1
Abstract:
The present invention relates to a composition, designed to administer bee venom and venlafaxine in combination, for preventing or treating pain induced by an anticancer agent, especially paclitaxel, and a therapeutic method using same. Administration of bee venom and venlafaxine in combination according to the present invention can prevent or treat allodynia induced by an anticancer agent, especially paclitaxel.
Inventors:
KIM SUN KWANG (KR)
LI DAXIAN (KR)
LI DAXIAN (KR)
Application Number:
PCT/KR2021/000314
Publication Date:
July 15, 2021
Filing Date:
January 11, 2021
Export Citation:
Assignee:
UNIV INDUSTRY COOPERATION GROUP KYUNG HEE UNIV (KR)
International Classes:
A61K35/64; A61K9/00; A61K31/137; A61P25/02; A61P25/04
Foreign References:
| KR20190139162A | 2019-12-17 | |||
| KR20160015526A | 2016-02-15 |
Other References:
LIM BONG-SOO, MOON HAK JIN, LI DONG XING, GIL MUNSOO, MIN JOON KI, LEE GISEOG, BAE HYUNSU, KIM SUN KWANG, MIN BYUNG-IL: "Effect of Bee Venom Acupuncture on Oxaliplatin-Induced Cold Allodynia in Rats", EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE, OXFORD UNIVERSITY PRESS, US, vol. 2013, no. 8, 1 January 2013 (2013-01-01), US, pages 1 - 8, XP055827649, ISSN: 1741-427X, DOI: 10.1155/2013/369324
LI DAXIAN, LEE JI, CHOI CHANG, KIM JAIHWAN, KIM SUN, KIM WOOJIN: "The Analgesic Effect of Venlafaxine and Its Mechanism on Oxaliplatin-Induced Neuropathic Pain in Mice", INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, vol. 20, no. 7, 3 April 2019 (2019-04-03), XP055827653, DOI: 10.3390/ijms20071652
JI-HYE LEE;DONG XING LI;HEERA YOON;DONGHYUN GO;FU SHI QUAN;BYUNG-IL MIN;SUN KWANG KIM: "Serotonergic mechanism of the relieving effect of bee venom acupuncture on oxaliplatin-induced neuropathic cold allodynia in rats", BMC COMPLEMENTARY AND ALTERNATIVE MEDICINE, BIOMED CENTRAL LTD., LONDON, GB, vol. 14, no. 1, 6 December 2014 (2014-12-06), GB, pages 471, XP021204903, ISSN: 1472-6882, DOI: 10.1186/1472-6882-14-471
LI DAXIAN, LEE JI, CHOI CHANG, KIM JAIHWAN, KIM SUN, KIM WOOJIN: "The Analgesic Effect of Venlafaxine and Its Mechanism on Oxaliplatin-Induced Neuropathic Pain in Mice", INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, vol. 20, no. 7, 3 April 2019 (2019-04-03), XP055827653, DOI: 10.3390/ijms20071652
JI-HYE LEE;DONG XING LI;HEERA YOON;DONGHYUN GO;FU SHI QUAN;BYUNG-IL MIN;SUN KWANG KIM: "Serotonergic mechanism of the relieving effect of bee venom acupuncture on oxaliplatin-induced neuropathic cold allodynia in rats", BMC COMPLEMENTARY AND ALTERNATIVE MEDICINE, BIOMED CENTRAL LTD., LONDON, GB, vol. 14, no. 1, 6 December 2014 (2014-12-06), GB, pages 471, XP021204903, ISSN: 1472-6882, DOI: 10.1186/1472-6882-14-471
Attorney, Agent or Firm:
HANOL INTELLECTUAL PROPERTY AND LAW (KR)
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