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Patent Searching and Data


Title:
COMPOSITION FOR PREVENTING OR TREATING BONE DISEASES COMPRISING COCKLE PROTEIN-DERIVED PEPTIDE AS ACTIVE INGREDIENT
Document Type and Number:
WIPO Patent Application WO/2018/147517
Kind Code:
A1
Abstract:
The present invention relates to an osteogenic promotion peptide comprising sequence number 1 (AWLNH) or sequence number 2 (PHDL), and a composition, for preventing or treating bone diseases, comprising the peptide. The peptide promotes osteoblast differentiation and thus can be utilized for preventing and treating bone diseases, particularly osteoporosis.

Inventors:
JE, Jae-Young (#304-401, 566 Sinseon-ro,Nam-gu, Busan, 48515, KR)
HYUNG, Jun-Ho (#9-1102, 17 Danggam-ro,Busanjin-gu, Busan, 47190, KR)
OH, Yun-Ok (#209-1402, 38-17 Yongho-ro,Nam-gu, Busan, 48517, KR)
Application Number:
KR2017/008288
Publication Date:
August 16, 2018
Filing Date:
August 01, 2017
Export Citation:
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Assignee:
PUKYONG NATIONAL UNIVERSITY INDUSTRY-UNIVERSITY COOPERATION FOUNDATION (365 Sinseon-ro, Nam-gu, Busan, 48547, KR)
International Classes:
C07K7/06; A61K38/07; A61K38/08; C07K5/10; C12N5/077
Foreign References:
US20040162415A12004-08-19
KR860002095B11986-11-25
Other References:
HYUNG, JUN-HO ET AL.: "steoblastogenic Activity of Ark Shell Protein Hydrolysates with Low Molecular Weight in Mouse Mesenchymal Stem Cells", ROYAL SOCIETY OF CHEMISTRY ADVANCES, vol. 6, 2016, pages 29365 - 29370
POUNTOS, IPPOKRATIS ET AL.: "The Role of Peptides in Bone Healing and Regeneration: a Systematic Review", BIOMED CENTRAL MEDICINE, vol. 14, 2016, pages 1 - 15, XP055534438
HYUNG, JUN-HO: "A Novel Peptide Purified from Low Molecular Weight Ark Shell (Scapharca subcrenata) Protein Hydrolysates Enhances Osteogenic Differentiation through Bone Morphogenetic Protein Signaling", MASTER'S THESIS, August 2016 (2016-08-01), pages 25 - 27 , 39-48
Attorney, Agent or Firm:
WIE, Byoung-Gap (Dae-young Bldg, 7F 7, Teheran-ro 33-gil,Gangnam-gu, Seoul, 06141, KR)
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