Title:
COMPOSITION FOR PREVENTING OR TREATING DISEASES CAUSED BY ANGIOGENESIS, CONTAINING HYDROXYCHALCONE COMPOUND AS ACTIVE INGREDIENT
Document Type and Number:
WIPO Patent Application WO/2014/007447
Kind Code:
A1
Abstract:
The present invention relates to a composition containing a hydroxychalcone compound, as an active ingredient, for inhibiting angiogenesis. The compounds of the present invention have remarkable angiogenesis inhibition effects in the chorioallantoic membrane model, and thus can be used as a pharmaceutical composition and a dietary supplement for preventing and treating diseases caused by angiogenesis.
Inventors:
LEE EUNG-SEOK (KR)
KIM JUNG-AE (KR)
KANG YOU-RA (KR)
KIM JUNG-AE (KR)
KANG YOU-RA (KR)
Application Number:
PCT/KR2012/011867
Publication Date:
January 09, 2014
Filing Date:
December 31, 2012
Export Citation:
Assignee:
UNIV YEUNGNAM IACF (KR)
KOREA HEALTH INDUSTRY DEV INST KHIDI (KR)
KOREA HEALTH INDUSTRY DEV INST KHIDI (KR)
International Classes:
A61K31/12; A61K31/36; A61P25/28; A61P35/00
Domestic Patent References:
| WO2001046110A2 | 2001-06-28 |
Foreign References:
| KR20030036993A | 2003-05-12 | |||
| JP2005533760A | 2005-11-10 |
Other References:
VARINSKA, L. ET AL.: "Anti-angiogenic activity of the flavonoid precursor 4-hydroxychalcone", EUROPEAN JOURNAL OF PHARMACOLOGY, vol. 691, 18 June 2012 (2012-06-18), pages 125 - 133
DANESE, S. ET AL.: "Angiogenesis as a novel component of inflammatory bowel disease pathogenesis", GASTROENTEROLOGY, vol. 130, 2006, pages 2060 - 2073, XP026190953, DOI: doi:10.1053/j.gastro.2006.03.054
DANESE, S. ET AL.: "Angiogenesis as a novel component of inflammatory bowel disease pathogenesis", GASTROENTEROLOGY, vol. 130, 2006, pages 2060 - 2073, XP026190953, DOI: doi:10.1053/j.gastro.2006.03.054
Attorney, Agent or Firm:
WIE, Byoung-Gab (KR)
위병갑 (KR)
위병갑 (KR)
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