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Title:
COMPOSITION FOR PREVENTING OR TREATING DISEASES CAUSED BY MITOCHONDRIAL DYSFUNCTION
Document Type and Number:
WIPO Patent Application WO/2020/262970
Kind Code:
A1
Abstract:
The present invention relates to a composition for preventing or treating diseases caused by mitochondrial dysfunction, containing berberine as an active ingredient, wherein berberine promotes mitophagy activity, and thus can be effectively used in the treatment of diseases caused by mitochondrial dysfunction.

Inventors:
YUN JEAN-HO (KR)
KIM DONG-HYUN (KR)
Application Number:
PCT/KR2020/008246
Publication Date:
December 30, 2020
Filing Date:
June 25, 2020
Export Citation:
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Assignee:
UNIV DONG A RES FOUND FOR IND ACAD COOP (KR)
International Classes:
A61K31/4375; A23L33/10; A61P25/28; G01N33/483
Domestic Patent References:
WO2017018382A12017-02-02
Foreign References:
US20030044776A12003-03-06
Other References:
CHUNHUI ZHAO, SU PING, LV CUI, GUO LIMIN, CAO GUOQIONG, QIN CHUNXIA, ZHANG WENSHENG: "Berberine Alleviates Amyloid β -Induced Mitochondrial Dysfunction and Synaptic Loss", OXIDATIVE MEDICINE AND CELLULAR LONGEVITY, vol. 2019, 7593608, 2 May 2019 (2019-05-02), pages 1 - 12, XP055770610, ISSN: 1942-0900, DOI: :10.1155/2019/7593608
YUN, JIN HO: "Exploring the physiological roles and modulation of mitophagy for the development of novel therapeutic approach", 2018 FALL INTERNATIONAL CONVENTION OF THE PHARMACEUTICAL SOCIETY OF KOREA, 19 October 2018 (2018-10-19), XP009525359
YUN, JIN HO: "Exploring the physiological roles and modulation of mitophagy for the development of novel therapeutic approach", (2018 MEDICAL SCIENCE AND ENGINEERING RESEARCH CENTER JOINT ACHIEVEMENT CONFERENCE), 23 October 2018 (2018-10-23)
YUN, JIN HO: "Exploring the physiological roles and molecular mechanism of in vivo mitophagy using novel mitophagy reporter system", 2019 KSBMB 10TH WINTER CONFERENCE, 9-11 JANUARY 2019, VIVALDI PARK, HONGCHEON, GANGWON-DO (KOREA), vol. 10, 11 January 2019 (2019-01-11), pages 40, XP009525333
YUN, JIN HO: "Exploring the physiological roles and modulation of mitophagy for the development of novel therapeutic approach", 2019 50TH KSSO ANNUAL SPRING CONFERENCE, 6 April 2019 (2019-04-06)
Attorney, Agent or Firm:
WIE, Byoung-Gap (KR)
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