Title:
COMPOSITION, FOR PREVENTING OR TREATING INFLAMMATORY DISEASE CAUSED BY ULTRAFINE DUST, COMPRISING CODIUM FRAGILE EXTRACT AS ACTIVE INGREDIENT
Document Type and Number:
WIPO Patent Application WO/2022/203440
Kind Code:
A1
Abstract:
The purpose of the present invention in order to solve the problem is to provide a composition, for preventing or treating an inflammatory disease caused by ultrafine dust, comprising a Codium fragile extract as an active ingredient. More specifically, by verifying that the Codium fragile extract has an excellent cytoprotective effect against cytotoxicity generated in nasal cells, lung cells, and neuronal cells, has a lipid peroxidation inhibitory effect in a brain tissue of an animal model exposed to ultrafine dust, and inhibits an inflammatory-related protein expression, the composition is prepared to prevent or treat a respiratory disease or a neurological disorder caused by ultrafine dust. The present invention may be utilized for a pharmaceutical composition for preventing or treating an inflammatory disease caused by ultrafine dust and a health functional food composition for preventing or relieving an inflammatory disease caused by ultrafine dust.
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Inventors:
HEO HO JIN (KR)
KIM TAE YOON (KR)
KIM TAE YOON (KR)
Application Number:
PCT/KR2022/004199
Publication Date:
September 29, 2022
Filing Date:
March 25, 2022
Export Citation:
Assignee:
INDUSTRY ACADEMICCOOPERATION FOUNDATIONGYEONGSANGNATIONAL UNIV (KR)
International Classes:
A23L33/105; A61K36/05; A61P11/00; A61P25/00; A61P29/00
Foreign References:
| KR20180064103A | 2018-06-14 | |||
| KR20190125923A | 2019-11-07 | |||
| KR20150071226A | 2015-06-26 | |||
| CN111991258A | 2020-11-27 | |||
| KR102013398B1 | 2019-08-22 |
Other References:
GIL HAN KIM, PARK SEON KYEONG, KANG JIN YONG, JONG MIN, KIM, SHIN EUN JIN, MOON JONG HYEON, LEE HYO LIM, JEONG HYE RIN, HEO HO JIN: "Protective effect of Codium fragile extract on fine dust (PM2.5)-induced toxicity in nasal cavity, lung, and brain cells", KOREAN J. FOOD SCI. TECHNOL, vol. 53, no. 2, 1 January 2021 (2021-01-01), pages 223 - 229, XP055973974, DOI: 10.9721/KJFST.2021.53.2.223
Attorney, Agent or Firm:
WIE, Byoung Gap (KR)
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