Title:
COMPOSITION FOR PREVENTING OR TREATING INFLUENZA, CONTAINING, AS ACTIVE INGREDIENT, ECKLONIA CAVA EXTRACT OR PHLOROTANNIN-BASED COMPOUND ISOLATED THEREFROM
Document Type and Number:
WIPO Patent Application WO/2018/088777
Kind Code:
A1
Abstract:
The present invention relates to a composition for preventing or treating influenza, containing, as an active ingredient, an Ecklonia cava extract or a phlorotannin-based compound isolated therefrom. The Ecklonia cava extract or dibenzo[1,4]dioxine-2,4,7,9-tetraol (compound 1), dioxinodehydroeckol (compound 2), and 6,6'-bieckol (compound 3), which are phlorotannin-based compounds isolated therefrom, are anti-virally active against avian influenza viruses or swine influenza viruses, and thus are expected to be usable in the development of a composition for preventing and treating influenza.
Inventors:
CHO TAE OH (KR)
OH WON KEUN (KR)
LEE JUN SIK (KR)
CHO GOANG WON (KR)
HA THIKIMQUY (VN)
CHO HYO MOON (KR)
OH WON KEUN (KR)
LEE JUN SIK (KR)
CHO GOANG WON (KR)
HA THIKIMQUY (VN)
CHO HYO MOON (KR)
Application Number:
PCT/KR2017/012550
Publication Date:
May 17, 2018
Filing Date:
November 07, 2017
Export Citation:
Assignee:
UNIV CHOSUN IACF (KR)
International Classes:
A61K36/03; A01N43/16; A23K20/121; A23L33/105; A61K31/357
Foreign References:
| KR20110086473A | 2011-07-28 |
Other References:
RYU, Y. B. ET AL.: "Influenza Virus Neuraminidase Inhibitory Activity of Phlorotannins from the Edible Brown Alga Ecklonja Cava", JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, vol. 59, no. 12, 2011, pages 6467 - 6473, XP055484257
PARK, J.-Y. ET AL.: "Dieckol, a SARS-CoV 3CLpro Inhibitor, Isolated from the Edible Brown Algae Ecklonia Cava", BIOORGANIC & MEDICINAL CHEMISTRY, vol. 21, no. 13, 2013, pages 3730 - 3737, XP028558882
ARTAN, M. ET AL.: "Anti-HIV-1 Activity of Phloroglucinol Derivative, 6,6'-bieckol, from Ecklonia Cava", BIOORGANIC & MEDICINAL CHEMISTRY, vol. 16, 2008, pages 7921 - 7926, XP024524908
KANNAN, R. R. R. ET AL.: "Acetylcholinesterase Inhibitory Activity of Pbloro-tanmns Isolated from the Brown Alga, Ecklonia Maxima (Osbeck) Papenfuss", FOOD RESEARCH INTERNATIONAL, vol. 54, 2013, pages 1250 - 1254, XP028750262
PARK, J.-Y. ET AL.: "Dieckol, a SARS-CoV 3CLpro Inhibitor, Isolated from the Edible Brown Algae Ecklonia Cava", BIOORGANIC & MEDICINAL CHEMISTRY, vol. 21, no. 13, 2013, pages 3730 - 3737, XP028558882
ARTAN, M. ET AL.: "Anti-HIV-1 Activity of Phloroglucinol Derivative, 6,6'-bieckol, from Ecklonia Cava", BIOORGANIC & MEDICINAL CHEMISTRY, vol. 16, 2008, pages 7921 - 7926, XP024524908
KANNAN, R. R. R. ET AL.: "Acetylcholinesterase Inhibitory Activity of Pbloro-tanmns Isolated from the Brown Alga, Ecklonia Maxima (Osbeck) Papenfuss", FOOD RESEARCH INTERNATIONAL, vol. 54, 2013, pages 1250 - 1254, XP028750262
Attorney, Agent or Firm:
GHONG-GAN INTERNATIONAL PATENT LAW FIRM (KR)
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