Login| Sign Up| Help| Contact|

Patent Searching and Data


Title:
COMPOSITION FOR PREVENTING OR TREATING MENOPAUSE, CONTAINING LACTOBACILLUS ACIDOPHILUS
Document Type and Number:
WIPO Patent Application WO/2018/030837
Kind Code:
A1
Abstract:
The present invention relates to: a novel Lactobacillus acidophilus YT1 strain (deposit number: KCCM11808P); and a composition for preventing, alleviating, or treating menopause, containing, as an active ingredient, Lactobacillus acidophilus including the novel strain. The present inventors have established an animal model for menopause through oophorectomy, confirmed changes of the distribution of intestinal microorganisms by the model, identified and isolated a novel Lactobacillus acidophilus strain among lactic acid bacteria of which the distribution is significantly reduced in the menopausal model, and confirmed effects, by means of the novel strain and previously reported Lactobacillus acidophilus strains, of alleviating menopausal symptoms, such as the inhibition of an increase in body fat, the inhibition of a loss in bone density, the inhibition of an increase in the sensitivity to pain, and the alleviation of depression. Therefore, it is expected that the composition containing the Lactobacillus acidophilus according to the present invention can be usable for a use of preventing, alleviating, or treating menopause.

Inventors:
NAM YOUNG DO (KR)
KIM YUN TAI (KR)
SHIN HEE SOON (KR)
LEE SO YOUNG (KR)
KIM JAE GOO (KR)
LIM EUN YEONG (KR)
SONG EUN JI (KR)
Application Number:
PCT/KR2017/008737
Publication Date:
February 15, 2018
Filing Date:
August 11, 2017
Export Citation:
Click for automatic bibliography generation   Help
Assignee:
KOREA FOOD RES INST (KR)
International Classes:
C12N1/20; A23L33/135; A61K8/99; A61K35/747; A61Q19/00; C12R1/23
Foreign References:
KR101279852B12013-07-09
US20090104167A12009-04-23
KR20150133284A2015-11-27
KR20150106478A2015-09-22
Other References:
DONDERS, GILBERT ET AL.: "Ultra-low-dose Estriol and Lactobacillus Acidophilus Vaginal Tablets (Gynoflor(®)) for Vaginal Atrophy in Postmenopausal Breast Cancer Patients on Aromatase Inhibitors: Pharmacokinetic, Safety, and Efficacy Phase I Clinical Study", BREAST CANCER RESEARCH AND TREATMENT, vol. 145, no. 2, 10 April 2014 (2014-04-10), pages 371 - 379, XP055500438, DOI: doi:10.1007/s10549-014-2930-x
See also references of EP 3498821A4
JOUR. TRANSL. MED., vol. 10, 2012, pages 253
Attorney, Agent or Firm:
LEE, Myoung-Jin (KR)
Download PDF: