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Patent Searching and Data


Title:
COMPOSITION FOR PREVENTING OR TREATING METABOLIC DISEASES
Document Type and Number:
WIPO Patent Application WO/2018/230931
Kind Code:
A3
Abstract:
The present invention relates to a composition for preventing or treating metabolic diseases and, more particularly, to a pharmaceutical composition and a food composition for preventing, alleviating, or treating metabolic diseases, comprising an extract of Gentianae Macrophyllae Radix as an active ingredient. The method of the present invention promotes AMPK activity; inhibits fat accumulation, fat granulation, lipogenesis transcription factor SREBP-1c activity, and lipogenic enzyme expression; and reduces body weight, fat tissue and liver tissue weight, blood glucose, triglycerides, and cholesterol content, and thus may be effectively used for preventing or treating metabolic diseases such as obesity, diabetes, hypertriglyceridemia, hypercholesterolemia, and the like.

Inventors:
YOON, You Sik (#3-207, 205 Nonhyeon-ro,Gangnam-gu, Seoul, 06270, KR)
JANG, Jae Woong (#405, 13 Suin-ro 2431beon-gi, Siheung-si Gyeonggi-do, 14982, KR)
LEE, Do Heon (#113-805, 155Dunsan-ro, Seo-gu, Daejeon, 35248, KR)
LEE, Sang yeon (291 Daehak-ro, Yuseong-gu, Daejeon, 34141, KR)
CHAE, Seyeon (7 Jeil-ro 98beon-gil, Sujeong-gu Seongnam-si, Gyeonggi-do, 13324, KR)
Application Number:
KR2018/006641
Publication Date:
December 20, 2018
Filing Date:
June 12, 2018
Export Citation:
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Assignee:
BIO-SYNERGY RESEARCH CENTER (#415, Jeongmunsul Building291, Daehak-ro,Yuseong-gu, Daejeon, 34141, KR)
CHUNG-ANG UNIVERSITY-ACADEMIC COOPERATION FOUNDATION (84 Heukseok-ro, Dongjak-gu, Seoul, 06974, KR)
KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY (291 Daehak-ro, Yuseong-gu, Daejeon, 34141, KR)
International Classes:
A61K36/515; A23L33/105
Foreign References:
KR20140147482A2014-12-30
KR20070033133A2007-03-26
CN105012769A2015-11-04
KR100720671B12007-05-15
KR101819221B12018-01-18
Other References:
KIM, HAN-SOO ET AL.: "Effects of Gentiana Scabra Bunge Var.buergeri Max Extract on Lipid Metabolism of Serum in Dietary Hyperlipidemic Rats", JOURNAL OF LIFE SCIENCE, vol. 8, no. 5, 1998, pages 532 - 536, XP053021468
Attorney, Agent or Firm:
LEE, Hee Sook (9th Fl, 11 Teheran-ro 33 gil,Gangnam-gu, Seoul, 06141, KR)
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