Title:
COMPOSITION FOR PREVENTING OR TREATING MULTIPLE SCLEROSIS, COLITIS AND PSORIASIS, CONTAINING DEHYDRODICONIFERYL ALCOHOL OR DERIVATIVE THEREOF AS ACTIVE INGREDIENT
Document Type and Number:
WIPO Patent Application WO/2015/108208
Kind Code:
A1
Abstract:
The present invention relates to a pharmaceutical composition containing dehydrodiconiferyl alcohol, a derivative thereof, optical isomers thereof, pharmaceutically acceptable salts thereof, or hydrates or solvates thereof, a treatment method using the same, and a use for the preparation thereof. The pharmaceutical composition, the treatment method using the same, and the use for the preparation thereof, according to the present invention, can be used for preventing or treating multiple sclerosis, colitis or psoriasis.
Inventors:
KIM SUNYOUNG (KR)
LEE JUNGHUN (KR)
LEE JUNGHUN (KR)
Application Number:
PCT/KR2014/000397
Publication Date:
July 23, 2015
Filing Date:
January 14, 2014
Export Citation:
Assignee:
VIROMED CO LTD (KR)
International Classes:
A61K31/343; A61P17/06; A61P29/00; C07D307/80
Domestic Patent References:
| WO2001001996A1 | 2001-01-11 |
Foreign References:
| KR20050054006A | 2005-06-10 |
Other References:
JEONG, E. J. ET AL.: "Inhibition of nitric oxide production in lipopolysaccharide-stimulated RAW264. 7 macrophage cells by lignans isolated from Euonymus alatus leaves and twigs", BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 21, no. 8, 15 April 2011 (2011-04-15), pages 2283 - 2286, XP055213825
LEE, J. ET AL.: "Dehydrodiconiferyl alcohol isolated from Cucurbita moschata shows anti-adipogenic and anti-lipogenic effects in 3T3-L1 cells and primary mouse embryonic fibroblasts", JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 287, no. 12, 16 March 2012 (2012-03-16), pages 8839 - 8851, XP055213831
LEE, JEONG HUN: "Molecular Cell Biological Characterization of Anti-adipogenic, Anti-inflammatory and Anti-oxidative Stress Activities of Dehydrodiconiferyl Alcohol", THESIS (PH.D., August 2013 (2013-08-01), GRADUATE SCHOOL OF SEOUL UNIVERSITY, COLLEGE OF NATURAL SCIENCES BIOLOGICAL SCIENCES, pages 1 - 185
LEE, J. ET AL.: "Dehydrodiconiferyl alcohol isolated from Cucurbita moschata shows anti-adipogenic and anti-lipogenic effects in 3T3-L1 cells and primary mouse embryonic fibroblasts", JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 287, no. 12, 16 March 2012 (2012-03-16), pages 8839 - 8851, XP055213831
LEE, JEONG HUN: "Molecular Cell Biological Characterization of Anti-adipogenic, Anti-inflammatory and Anti-oxidative Stress Activities of Dehydrodiconiferyl Alcohol", THESIS (PH.D., August 2013 (2013-08-01), GRADUATE SCHOOL OF SEOUL UNIVERSITY, COLLEGE OF NATURAL SCIENCES BIOLOGICAL SCIENCES, pages 1 - 185
Attorney, Agent or Firm:
AHN, So-Young (KR)
안소영 (KR)
안소영 (KR)
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