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Title:
COMPOSITION FOR PREVENTING OR TREATING PERIODONTAL DISEASES COMPRISING AS ACTIVE INGREDIENT SCUTELLARIA BAICALENSIS EXTRACT TREATED WITH ENZYME ISOLATED FROM ASPERGILLUS NIGER
Document Type and Number:
WIPO Patent Application WO/2019/050063
Kind Code:
A1
Abstract:
The present invention relates to a composition for preventing or treating periodontal diseases, the composition comprising, as an active ingredient, a Scutellaria baicalensis extract treated with an Aspergillus niger-derived enzyme. The Scutellaria baicalensis extract treated with the Aspergillus niger-derived enzyme according to the present invention promotes mineralization of osteoblasts, stimulates proliferation of periodontal ligament cells, and exhibits excellent activity in prevention or treatment of periodontal diseases by inhibiting expression of interleukin-1β, TNF-α (tumor necrosis factor-alpha), and MMP-1 (matrix metalloproteinase-1), thereby being able to be usefully used as a pharmaceutical composition, functional health food, or the like.

Inventors:
YI, Tae Hoo (5F 807, Nonhyeon-ro,Gangnam-gu, Seoul, 06032, KR)
LEE, Hyun Myung (105-1101, 53 Yeongtong-ro 514beon-gil,,Yeongtong-gu, Suwon-si, Gyeonggi-do, 16712, KR)
Application Number:
KR2017/009811
Publication Date:
March 14, 2019
Filing Date:
September 07, 2017
Export Citation:
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Assignee:
TAEYI LIFESCIENCE INC. (501 College of Agriculture Life Sciences, 1732 Deogyeong-daero,,Giheung-gu, Yongin-si, Gyeonggi-do, 17104, KR)
International Classes:
A61K36/539; A23L33/105
Foreign References:
KR20110060154A2011-06-08
US20030147980A12003-08-07
KR20130132172A2013-12-04
KR20160016127A2016-02-15
KR20110060238A2011-06-08
Attorney, Agent or Firm:
AHN, Chang Woo (4F 1768-1, Nambusunhwan-ro,Gwanak-gu, Seoul, 08786, KR)
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