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Title:
COMPOSITION FOR PREVENTION, TREATMENT OR AMELIORATION OF PROSTATE DISEASE COMPRISING EXTRACTS OF ACANTHOPANACIS CORTEX, PHRAGMITIS RHIZOMA, AND PINUS DENSIFLORA AS ACTIVE INGREDIENT
Document Type and Number:
WIPO Patent Application WO/2019/124757
Kind Code:
A1
Abstract:
The present invention relates to a composition for prevention, treatment, or amelioration of prostate disease which comprises extracts of Acanthopanacis Cortex, Phragmitis Rhizoma, and Pinus densiflora as active ingredients. A combined extract of Acanthopanacis Cortex, Phragmitis Rhizoma, and Pinus densiflora of the present invention has the effect of inhibiting activity of 5-α reductases related to prostatic hyperplasia and by using a natural plant-derived ingredient, has the advantage of having little or no side effects of reducing male sexual function caused by using an existing synthetic compound. In addition, since it has been verified in the present invention that the combined extract obtained by mixing the extracts of Acanthopanacis Cortex, Phragmitis Rhizoma, and Pinus densiflora in an appropriate ratio, rather than the respective extracts alone, has a remarkably excellent effect of inhibiting the activity of 5-α reductases. Accordingly, it is expected that the present invention will contribute to the national economy by replacing synthetic compounds that are reliant on importation thereof for the prevention or treatment of prostatic hyperplasia, and may be used in various fields such as the medicine, quasi drug, functional biomaterial, and functional food material fields as a prophylactic or therapeutic agent for prostate hyperplasia with reduced side effects of existing 5-α reductase inhibitors.

Inventors:
LEE MIN WON (KR)
YOON KYU HYEONG (KR)
LEE YOON OK (KR)
YOUN SUNG HYE (KR)
YOON JAE SEUNG (KR)
Application Number:
PCT/KR2018/014166
Publication Date:
June 27, 2019
Filing Date:
November 19, 2018
Export Citation:
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Assignee:
GENOME & MEDICINE CO LTD (KR)
International Classes:
A61K36/254; A23L33/105; A61K36/15; A61K36/899; A61P13/08
Foreign References:
KR20130081131A2013-07-16
KR20060067255A2006-06-19
KR20140015199A2014-02-06
KR20160084175A2016-07-13
KR20160125090A2016-10-31
JPH07278003A1995-10-24
KR101917733B12018-11-13
Attorney, Agent or Firm:
KIM, Joonghyo (KR)
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