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Patent Searching and Data


Title:
COMPOSITION FOR PROMOTING GLP-1 SECRETION, AND METHOD FOR MANUFACTURING SAME
Document Type and Number:
WIPO Patent Application WO/2017/159725
Kind Code:
A1
Abstract:
The present invention provides a composition useful for activating GLP-1 secretion. This composition can be configured from a specific compound such as compound (1). The specific compound of such description can be obtained with good efficiency by heat treating a bitter gourd component (e.g., bitter gourd puree or the like), for example.

Inventors:
WATANABE HIROSHI (JP)
SUZUKI TOSHIHIDE (JP)
ABE KEIICHI (JP)
HORIKAWA MANABU (JP)
AZUMA TOSHIAKI (JP)
Application Number:
JP2017/010362
Publication Date:
September 21, 2017
Filing Date:
March 15, 2017
Export Citation:
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Assignee:
SUNTORY HOLDINGS LTD (JP)
International Classes:
A61K31/575; A61K31/58; A61K31/7048; A61K36/42; A61P3/04; A61P3/08; A61P3/10; A61P43/00
Foreign References:
JP2011020925A2011-02-03
Other References:
TING-NI HUANG ET AL.: "Role of GLP-1 in the Hypoglycemic Effects of Wild Bitter Gourd", EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE, vol. 2013, no. 625892, 2013, pages 1 - 13, XP055422866
LU WEI ET AL.: "Increase in the free radical scavenging capability of bitter gourd by a heat-drying process", FOOD & FUNCTION, vol. 4, no. 12, 2013, pages 1850 - 5, XP055422868
MASAKI WATANABE ET AL.: "Tonyobyo Rat no Shishitsu Taisha ni Oyobosu Nigauri Funmatsu Choseiji ni Okeru Kanso Shoriho no Eikyo", PROCEEDINGS OF JAPANESE SOCIETY OF FOOD SCIENCE AND TECHNOLOGY, vol. 50, no. 67, 2003, pages 3Ga4
ZHEN-JIE LI ET AL.: "Two New Cucurbitane Triterpenoids from Immature Fruits of Momordica charantia", HELVETICA CHIMICA ACTA, vol. 98, no. 10, 2015, pages 1456 - 61
PING-CHUN HSIAO ET AL.: "Antiproliferative and hypoglycemic cucurbitane-type glycosides from the fruits of Momordica charantia", JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, vol. 61, no. 12, 2013, pages 2979 - 86, XP055422871
LIVA HARINANTENAINA ET AL.: "Momordica charantia constituents and antidiabetic screening of the isolated major compounds", CHEM PHARM BULL, vol. 54, no. 7, 2006, pages 1017 - 21, XP008139769
DANIEL BISRAT MEKURIA ET AL.: "Cucurbitane triterpenoid oviposition deterrent from Momordica charantia to the leafminer, Liriomyza trifolii", BIOSCIENCE, BIOTECHNOLOGY, AND BIOCHEMISTRY, vol. 69, no. 9, 2005, pages 1706 - 10, XP055422878
NGUYEN XUAN NHIEM ET AL.: "Cucurbitane-type triterpene glycosides from the fruits of Momordica charantia", MAGNETIC RESONANCE IN CHEMISTRY, vol. 48, no. 5, 2010, pages 392 - 6, XP055422885
QING YAN LIA ET AL.: "A new cucurbitane triterpenoid from Momordica charantia", CHINESE CHEMICAL LETTERS, vol. 18, no. 7, 2007, pages 843 - 5, XP022139807
Attorney, Agent or Firm:
IWATANI, Ryo (JP)
Tatsu Iwatani (JP)
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