Title:
COMPOSITION PROMOTING IL-12 PRODUCTION
Document Type and Number:
WIPO Patent Application WO/2005/039321
Kind Code:
A1
Abstract:
It is intended to clarify the relationship between Agaricus blazei and IL-12 and thus provide a food having a novel function with the use of Agaricus blazei as the starting material. A composition promoting IL-12 production characterized by containing, as the main components, a lactic acid fermentation product which is obtained by adding a lactic acid bacterium to Agaricus blazei and thus effecting lactic acid fermentation and an enzymatic digestion product which is obtained by an enzymatic treatment with the addition of hemicellulase.
Inventors:
UMINO YUKI
KATO MARIA
KOIKE TAISUKE
NAKAMURA HITOMI
HORIUCHI ISAO
KATO MARIA
KOIKE TAISUKE
NAKAMURA HITOMI
HORIUCHI ISAO
Application Number:
PCT/JP2004/002624
Publication Date:
May 06, 2005
Filing Date:
March 03, 2004
Export Citation:
Assignee:
JAPAN APPLIED MICROBIOLOGY RES (JP)
UMINO YUKI
KATO MARIA
KOIKE TAISUKE
NAKAMURA HITOMI
HORIUCHI ISAO
UMINO YUKI
KATO MARIA
KOIKE TAISUKE
NAKAMURA HITOMI
HORIUCHI ISAO
International Classes:
A23L1/30; A61K36/00; A61K36/07; C12P1/04; (IPC1-7): A23L1/30; A61K35/78
Foreign References:
| JPH10287584A | 1998-10-27 | |||
| JP2002136277A | 2002-05-14 |
Other References:
SAITO K, ET AL: "Soluble branched Beta-(1,4)glucans from acetobacter species show strong activities to induce interleukin-12 in vitro and inhibit T-helper 2 cellular response with immunoglobulin E production in vivo", THE JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 278, no. 40, October 2003 (2003-10-01), pages 38571 - 38578, XP002979654
KODAMA N, ET AL: "Effects of D-fraction, a polysaccharide from grifola frondosa on tumor growth involve activation of NK cells", BIOL. PHARM. BULL, vol. 25, no. 12, 2002, pages 1647 - 1650, XP002979655
KODAMA N, ET AL: "Effects of D-fraction, a polysaccharide from grifola frondosa on tumor growth involve activation of NK cells", BIOL. PHARM. BULL, vol. 25, no. 12, 2002, pages 1647 - 1650, XP002979655
Attorney, Agent or Firm:
Shimizu, Yoshihiro (Yashiro Building 14-4, Takadanobaba 2-chom, Shinjuku-ku Tokyo, JP)
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