Title:
COMPOSITION FOR PROMOTING LOCAL MUSCLE GROWTH OR SLOWING DOWN OR PREVENTING LOCAL MUSCLE ATROPHY AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2019/178759
Kind Code:
A1
Abstract:
Disclosed is a composition for promoting local muscle growth or slowing down or preventing local muscle atrophy, which composition contains a polypeptide in the C2 region of the enterotoxin Staphylococcus aureus and a myostatin polypeptide. By means of the composition, the defect in the prior art of only systemic muscle growth being possible has been overcome so as to achieve effects of promoting local muscle growth, or slowing down or preventing local muscle atrophy.
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Inventors:
HUNG CHENG-HSIAO (CN)
JAN HSUN-JIN (CN)
JAN HSUN-JIN (CN)
Application Number:
PCT/CN2018/079716
Publication Date:
September 26, 2019
Filing Date:
March 21, 2018
Export Citation:
Assignee:
VICTORIA BIOMEDICAL HOLDINGS CO LTD (AI)
International Classes:
A61K38/18; A61K39/085; A61P21/06
Foreign References:
| CN102793079A | 2012-11-28 | |||
| CN102114239A | 2011-07-06 | |||
| CN102741276A | 2012-10-17 | |||
| CN101522707A | 2009-09-02 | |||
| TWI540968B | 2016-07-11 |
Other References:
DATABASE NCBI 11 January 2018 (2018-01-11), "exotoxin[Staphylococcus aureus", XP55636312, Database accession no. WP_077156035. 1
DATABASE GenBank 16 April 2001 (2001-04-16), REN, K.: "enterotoxin H [Staphylococcus aureus", XP55636324, Database accession no. AAA19777.1
LI SHU-WEI, OUYANG HONG-SHENG, WANG XIAO-XIA: "Progress of study on myostatin gene", PROGRESS IN VETERINARY MEDICINE, vol. 25, no. 4, 20 July 2004 (2004-07-20), pages 29 - 31, XP055738230, ISSN: 1007-5088, DOI: 10.16347/j.cnki.1007-5088.2004.04.009
HAO WEMBO: "Myostatin and its inhibitor", CHINESE JOURNAL OF BIOLOGICALS, vol. 20, no. 3, 31 March 2007 (2007-03-31), pages 230 - 232, XP009523383, ISSN: 1004-5503, DOI: 10.13200/j.cjb.2007.03.83.haowb.025
WHITTEMORE ET AL., BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, vol. 300, 2003, pages 965 - 971
See also references of EP 3769779A4
DATABASE GenBank 16 April 2001 (2001-04-16), REN, K.: "enterotoxin H [Staphylococcus aureus", XP55636324, Database accession no. AAA19777.1
LI SHU-WEI, OUYANG HONG-SHENG, WANG XIAO-XIA: "Progress of study on myostatin gene", PROGRESS IN VETERINARY MEDICINE, vol. 25, no. 4, 20 July 2004 (2004-07-20), pages 29 - 31, XP055738230, ISSN: 1007-5088, DOI: 10.16347/j.cnki.1007-5088.2004.04.009
HAO WEMBO: "Myostatin and its inhibitor", CHINESE JOURNAL OF BIOLOGICALS, vol. 20, no. 3, 31 March 2007 (2007-03-31), pages 230 - 232, XP009523383, ISSN: 1004-5503, DOI: 10.13200/j.cjb.2007.03.83.haowb.025
WHITTEMORE ET AL., BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, vol. 300, 2003, pages 965 - 971
See also references of EP 3769779A4
Attorney, Agent or Firm:
BEIJING HUI & XIN IP LAW OFFICE (CN)
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