COMPOSITION FOR PROTECTING LIVER COMPRISING DANDELION EXTRACT AND LEMON BALM EXTRACT

WIPO Patent Application WO/2019/013495

A3

The present invention can effectively protect a liver from oxidative stress caused by liver damage by significantly reducing the aspartate aminotransferase (AST) and alanine aminotransferase (ALT) values, which are widely known as indicators of liver damage when applied to liver toxicity animal models. The present invention relates to a composition for protecting a liver comprising a dandelion extract and a lemon balm extract as active ingredients that can be usefully used for preventing, ameliorating or treating liver damage, wherein the composition is characterized by comprising a dandelion extract and a lemon balm extract as active ingredients.

CHAE SOO WAN (KR)
SO BYOUNG OK (KR)
JUNG SU JIN (KR)

PCT/KR2018/007681

March 28, 2019

July 06, 2018

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PHYTONUTRIMEDI CO LTD (KR)

A61K36/288; A23L33/105; A61K36/53

JP2013199447A	2013-10-03
KR20100082129A	2010-07-16

KIM SUNG HOON ET AL: "- Taraxacum Mongolicum H. Suppress Hepatoprotective Activity by Increasing Liver Antioxidant Enzyme in Carbon Tetrachloride(CCl_4)-induced Hepatotoxicity in Rats", KOREAN JOURNAL OF ORIENTAL PHYSIOLOGY AND PATHOLOGY, vol. 24, no. 3, 2010, pages 439 - 445, XP053004994
LIU ET AL.: "Protective effect of dandelion extracts on ethanol- induced acute hepatotoxicity in C57BL/6 mice", JOURNAL OF FOOD SCIENCE AND NUTRITION, 2008, pages 269 - 275, XP053005320, DOI: doi:10.3746/jfn.2008.13.4.269
SIEF ET AL.: "Ameliorative role of melissa officinalis against hepatorenal toxicities of organophosphorus malathion in male rats", MOJ TOXICOLOGY, 2015, pages 103 - 109, XP055584512

SEONG, Nak Hoon (KR)

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