Title:
COMPOSITION FOR RECONSTITUTING HUMAN SKIN TISSUE HAVING HAIR FOLLICLES, HUMAN SKIN TISSUE MODEL ANIMAL, AND PRODUCTION METHOD THEREOF
Document Type and Number:
WIPO Patent Application WO/2020/105643
Kind Code:
A1
Abstract:
The present invention provides: a composition for reconstituting human skin tissue having hair follicles, the composition characterized by containing human epidermal cells and human dermal cells, the human dermal cells containing cell groups of human hair papilla derived from non-embryos via spheroid formation; and a human skin tissue model animal to which said composition is applied. The invention also provides a method for producing said composition and animal.
Inventors:
YOSHIDA YUZO (JP)
SOMA TSUTOMU (JP)
KISHIMOTO JIRO (JP)
MATSUZAKI TAKASHI (JP)
SOMA TSUTOMU (JP)
KISHIMOTO JIRO (JP)
MATSUZAKI TAKASHI (JP)
Application Number:
PCT/JP2019/045303
Publication Date:
May 28, 2020
Filing Date:
November 19, 2019
Export Citation:
Assignee:
SHISEIDO CO LTD (JP)
International Classes:
A01K67/027; C12N5/071
Foreign References:
| JP2015165823A | 2015-09-24 | |||
| JP2015213495A | 2015-12-03 | |||
| JP2016016267A | 2016-02-01 | |||
| JP2005132813A | 2005-05-26 | |||
| JP2015097524A | 2015-05-28 |
Other References:
TSUYAMA YOICHI: "Matrixome technology supports the development of regenerative medicine", REGENERATIVE MEDICINE, vol. 17, no. 3, 31 August 2018 (2018-08-31), pages 71 - 75, XP009521327
EHAMA R. ET AL.: "Hair follicle regeneration using grafted rodent and human cells", J INVEST DERMATOL, vol. 127, no. 9, 12 April 2007 (2007-04-12), pages 2106 - 2115, XP055088241, DOI: 10.1038/sj.jid.5700823
NOBURO SATO ET AL., NATURE MEDICINE, vol. 10, no. 1, January 2004 (2004-01-01)
See also references of EP 3884771A4
EHAMA R. ET AL.: "Hair follicle regeneration using grafted rodent and human cells", J INVEST DERMATOL, vol. 127, no. 9, 12 April 2007 (2007-04-12), pages 2106 - 2115, XP055088241, DOI: 10.1038/sj.jid.5700823
NOBURO SATO ET AL., NATURE MEDICINE, vol. 10, no. 1, January 2004 (2004-01-01)
See also references of EP 3884771A4
Attorney, Agent or Firm:
AOKI, Atsushi et al. (JP)
Download PDF: