COMPOSITION FOR REGENERATIVE THERAPY AND METHOD OF PRODUCING COMPOSITION FOR REGENERATIVE THERAPY

WIPO Patent Application WO/2020/130038

A1

[Problem] To provide: a composition for regenerative therapy which focuses on a specific kind of cytokine and the concentration thereof in cytokines which are contained in a stem cell culture supernatant obtained by culturing dental pulp-derived stem cells; and a method of producing the composition for regenerative therapy. [Solution] A composition for regenerative therapy according to the present invention is a generic alternative technology for diseases that are intractable in conventional medical treatments, and has a specific concentration range of a vascular endothelial growth factor (VEGF) in cytokines contained in dental pulp-derived stem cell culture supernatant when the regenerative therapy is performed by using the composition for regenerative therapy that employs dental pulp-derived stem cells. Thus, a cytokine which is considered beneficial for regenerative therapy acts effectively on cells, so that a composition for regenerative therapy which has good cell proliferation ability and is excellent for regenerative therapy can be efficiently provided.

KOBAYASHI TAKAYUKI (JP)
ITAYA TOSHIMITSU (JP)

PCT/JP2019/049600

June 25, 2020

December 18, 2019

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GENESIS INC (JP)

A61K33/06; A61P1/02; A61K35/22; A61K38/19; A61K38/30; A61P1/16; A61P3/10; A61P9/10; A61P15/00; A61P15/10; A61P15/12; A61P17/00; A61P17/14; A61P19/02; A61P21/00; A61P25/16; A61P25/28; A61P27/02; A61P27/04; A61P35/00; A61P37/08; A61P43/00; C12N1/00; C12N5/0775

WO2011118795A1	2011-09-29
WO2013118877A1	2013-08-15
WO2010021412A1	2010-02-25
WO2015111712A1	2015-07-30

HATA, Masanori (JP)

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