Title:
COMPOSITION FOR SKIN WHITENING COMPRISING TNFRSF14-INHIBITING MATERIAL, AND METHOD FOR SCREENING TNFRSF14-INHIBITING MATERIAL
Document Type and Number:
WIPO Patent Application WO/2018/056581
Kind Code:
A1
Abstract:
The present specification discloses a composition for skin whitening comprising a TNFRSF14 expression- or activity-inhibiting material as an active ingredient, and a method for screening the TNFRSF14 expression- or activity-inhibiting material. The composition comprising the TNFRSF14 expression- or activity-inhibiting material as an active ingredient can provide an excellent whitening effect by decreasing the melanin content in the skin. Also, the screening method confirms the relative expression inhibition level of the TNFRSF14 gene, thereby simply screening a skin whitening material.
Inventors:
KIM KYUHAN (KR)
LEE TAE RYONG (KR)
CHO EUN-GYUNG (KR)
LEE TAE RYONG (KR)
CHO EUN-GYUNG (KR)
Application Number:
PCT/KR2017/008922
Publication Date:
March 29, 2018
Filing Date:
August 17, 2017
Export Citation:
Assignee:
AMOREPACIFIC CORP (KR)
International Classes:
A61K8/60; A61K8/14; A61K48/00; A61Q19/02; G01N33/50; G01N33/68
Domestic Patent References:
| WO2015160147A1 | 2015-10-22 |
Foreign References:
| KR20090010234A | 2009-01-29 | |||
| KR101207561B1 | 2012-12-04 |
Other References:
REEMANN, PAULA ET AL.: "Melanocytes in the Skin-comparative Whole Transcriptome Analysis of Main Skin Cell Types", PLOS ONE, vol. 9, no. 12, 29 December 2014 (2014-12-29), pages el 15717, XP055498889
SPANJAARD, REMCO A. ET AL.: "Tumor Necrosis Factor Receptor Superfamily Member TROY Is a Novel Melanoma Biomarker and Potential Therapeutic Target", INTERNATIONAL JOURNAL OF CANCER, vol. 120, no. 6, 22 December 2006 (2006-12-22), pages 1304 - 1310, XP002448314
SPANJAARD, REMCO A. ET AL.: "Tumor Necrosis Factor Receptor Superfamily Member TROY Is a Novel Melanoma Biomarker and Potential Therapeutic Target", INTERNATIONAL JOURNAL OF CANCER, vol. 120, no. 6, 22 December 2006 (2006-12-22), pages 1304 - 1310, XP002448314
Attorney, Agent or Firm:
KIM, Sun-young (KR)
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