Title:
COMPOSITION FOR TREATING CENTRAL NERVOUS SYSTEM DISEASES, METHOD FOR PRODUCING COMPOSITION FOR TREATING CENTRAL NERVOUS SYSTEM DISEASES, AND METHOD FOR PRODUCING THERAPEUTIC FORMULATION FOR CENTRAL NERVOUS SYSTEM DISEASES
Document Type and Number:
WIPO Patent Application WO/2022/049977
Kind Code:
A1
Abstract:
The present invention addresses the problem of providing: a composition for treating central nervous system diseases; a method for producing a composition for treating central nervous system diseases; and a method for producing/storing a therapeutic formulation for central nervous system diseases. The problem is solved by means of a composition for treating central nervous system diseases, the composition containing synovium-derived mesenchymal stem cells cultured in a serum-free medium.
Inventors:
KONISHI HIROMU (JP)
MATSUMOTO MASAYA (JP)
IWAMOTO KAORI (JP)
MIYAKE MEGUMI (JP)
TSUJI KOICHIRO (JP)
MATSUMOTO MASAYA (JP)
IWAMOTO KAORI (JP)
MIYAKE MEGUMI (JP)
TSUJI KOICHIRO (JP)
Application Number:
PCT/JP2021/028948
Publication Date:
March 10, 2022
Filing Date:
August 04, 2021
Export Citation:
Assignee:
TWO CELLS CO LTD (JP)
International Classes:
A61K35/32; A61P21/00; A61P25/00; A61P25/14; A61P25/16; A61P25/28; A61K35/28; C12N5/0775
Domestic Patent References:
| WO2018123968A1 | 2018-07-05 | |||
| WO2009034708A1 | 2009-03-19 | |||
| WO2005007176A1 | 2005-01-27 | |||
| WO2007080919A1 | 2007-07-19 | |||
| WO2011111787A1 | 2011-09-15 | |||
| WO2015016357A1 | 2015-02-05 |
Foreign References:
| JP2012157263A | 2012-08-23 |
Other References:
NISHINA, HIROSHI: "Development of serum-free cell culture method of human dermal stem cells and transplant indication to spinal cord injury model in rats", JAPANESE JOURNAL OF TRANSPLANTATION, vol. 45, no. 3, 1 January 2010 (2010-01-01), JP , pages 301 - 302, XP009534945, ISSN: 0578-7947
JINCHANG SHAO, SHINICHI HASEGAWA, YUKIO KATO, TSUJI KOICHIRO: "Development of chemically defined serum-free media: SKT series (STK1, STK2, STK3) for human mesenchymal stem cell", THE CHEMICAL TIMES, vol. 2020, no. 2, 1 April 2020 (2020-04-01), Japan , pages 17 - 22, XP009534946, ISSN: 0285-2446
BASSO ET AL.: "A sensitive and reliable locomotor rating scale for open field testing in rats", J. NEUROTRAUMA, vol. 12, 1995, pages 1 - 21, XP009036806
JINCHANG SHAO, SHINICHI HASEGAWA, YUKIO KATO, TSUJI KOICHIRO: "Development of chemically defined serum-free media: SKT series (STK1, STK2, STK3) for human mesenchymal stem cell", THE CHEMICAL TIMES, vol. 2020, no. 2, 1 April 2020 (2020-04-01), Japan , pages 17 - 22, XP009534946, ISSN: 0285-2446
BASSO ET AL.: "A sensitive and reliable locomotor rating scale for open field testing in rats", J. NEUROTRAUMA, vol. 12, 1995, pages 1 - 21, XP009036806
Attorney, Agent or Firm:
HARAKENZO WORLD PATENT & TRADEMARK (JP)
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