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Title:
COMPOSITION FOR TREATING FINE DUST-CAUSED SKIN CELL DAMAGE, COMPRISING PRUNUS MUME FLOWER EXTRACT
Document Type and Number:
WIPO Patent Application WO/2019/059527
Kind Code:
A1
Abstract:
Disclosed in the present specification is a composition comprising a Prunus mume flower extract as an effective ingredient for treating fine dust-caused skin damage, wherein the expression of IL-36G (NM_019618), which is a gene having an expression level affected by fine dust in skin cells, is regulated to a novel level. By using the composition for treating fine dust-caused skin damage, gene expression changed by fine dust can return to a normal level to treat skin cell damage.

Inventors:
KIM HYOUNG-JUNE (KR)
SHIM JINSUP (KR)
LEE TAE RYONG (KR)
Application Number:
PCT/KR2018/009253
Publication Date:
March 28, 2019
Filing Date:
August 13, 2018
Export Citation:
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Assignee:
AMOREPACIFIC CORP (KR)
International Classes:
A61K8/9789; A23L33/105; A61K36/73; A61Q19/00
Foreign References:
KR20110051880A2011-05-18
KR20130035408A2013-04-09
Other References:
AHN, YONG CHAN: "2 in 1 Plum Blossom Moisturizing and Peeling, Removing Keratin and Keeping Moisture", BEAUTY NURY - COSMETICS NEWSPAPER, 10 March 2017 (2017-03-10), pages 1, Retrieved from the Internet
JUNG, BOCK-GIE ET AL.: "Fermented Maesil (Prunus mume) with Probiotics Inhibits Development of Atopic Dermatitis-like Skin Lesions in NC/Nga Mice", VETERINARY DERMATOLOGY, vol. 21, no. 2, 2010, pages 184 - 191, XP055584925
D'ERME, ANGELO MASSIMILIANO ET AL.: "IL -36gamma ( IL -IF9) Is a Biomarker for Psoriasis Skin Lesions", JOURNAL OF INVESTIGATIVE DERMATOLOGY, vol. 135, no. 4, 2015, pages 1025 - 1032, XP055584929
Attorney, Agent or Firm:
KIM, Sun-young (KR)
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