COMPOSITION FOR TREATMENT OF ACUTE PSEUDOMEMBRANOUS COLITIS

Title:

COMPOSITION FOR TREATMENT OF ACUTE PSEUDOMEMBRANOUS COLITIS

Document Type and Number:

WIPO Patent Application WO/2011/132943

Kind Code:

A9

Abstract:

Disclosed is a composition for treatment of pseudomembranous colitis including a coprisin peptide derivative CopA3 (HL) having the following amino acid sequence, as an active ingredient: L-L-C-A-L-R-K-K. According to the present disclosure, the coprisin peptide derivative CopA3 (HL) does not show antibiotic effects upon effective colon microorganisms such as Bifidobacterium, Lactobacillus, or the like, while having antibiotic effects specific to Cd bacteria as a pathogenic microorganism. Effects of CopA3 (HL) for inhibiting growth of Cd bacteria have been verified through animal testing, and Cd bacteria-derived intestinal inflammation and villous necrosis processes are effectively relieved.

Inventors:

HWANG JAE SAM (KR)
YUN EUN YEONG (KR)
KIM SEONG RYEOL (KR)
NAM SEONG HUI (KR)
AHN MI YEONG (KR)
CHOI YEONG CHEOL (KR)
KIM HO (KR)
NAM HYO JUNG (KR)
KANG JIN KU (KR)
KIM IN WOO (KR)

Application Number:

PCT/KR2011/002845

Publication Date:

April 05, 2012

Filing Date:

April 20, 2011

Export Citation:

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Assignee:

REPUBLIC KOREA MAN RURAL DEV (KR)
UNIV DAEJIN CT EDUCATIONAL IND COOPERATION (KR)
HWANG JAE SAM (KR)
YUN EUN YEONG (KR)
KIM SEONG RYEOL (KR)
NAM SEONG HUI (KR)
AHN MI YEONG (KR)
CHOI YEONG CHEOL (KR)
KIM HO (KR)
NAM HYO JUNG (KR)
KANG JIN KU (KR)
KIM IN WOO (KR)

International Classes:

A61K38/08; A61P1/00; A61P1/04

Attorney, Agent or Firm:

SELIM INTELLECTUAL PROPERTY LAW FIRM (Seolim Bldg.649-10, Youksam-dong, Gangnam-gu, Seoul 135-080, KR)

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