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Title:
COMPOSITION FOR TREATMENT OF DISEASES RELATED TO REMOVAL OF EXTRACELLULAR ALPHA-SYNUCLEIN AND METHOD FOR SCREENING THERAPEUTIC AGENT FOR SAID DISEASES
Document Type and Number:
WIPO Patent Application WO/2014/092227
Kind Code:
A1
Abstract:
The present invention relates to a composition for treatment of diseases related to the removal of extracellular alpha-synuclein and to a method for screening a therapeutic agent for said diseases.

Inventors:
LEE SEUNG JAE (KR)
BAE EUN JIN (KR)
LEE HE JIN (KR)
Application Number:
PCT/KR2012/011024
Publication Date:
June 19, 2014
Filing Date:
December 17, 2012
Export Citation:
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Assignee:
UNIV KONKUK IND COOP CORP (KR)
International Classes:
C07K16/18; A61K39/395; A61P25/16; G01N33/15
Domestic Patent References:
WO2006020581A22006-02-23
Foreign References:
KR20120090672A2012-08-17
US20070232556A12007-10-04
Other References:
LEE, HE-JIN ET AL.: "Enzyme-linked immunosorbent assays for a-synuclein with species and multimeric state specificities", J. NEUROSCI. METHODS, vol. 199, no. 2, 31 May 2011 (2011-05-31), pages 249 - 257, XP028238899, DOI: doi:10.1016/j.jneumeth.2011.05.020
FELLNER, LISA ET AL.: "Toll-like receptor 4 is required for a-synuclein dependent activation ofmicroglia and astroglia", GLIA, vol. 61, no. 3, 25 October 2012 (2012-10-25), pages 349 - 360
Attorney, Agent or Firm:
SU INTELLECTUAL PROPERTY (KR)
특허법인 수 (KR)
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