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Title:
COMPOSITIONS AND COMBINATIONS FOR USE AS FOOD SUPPLEMENTS FOR ANIMALS
Document Type and Number:
WIPO Patent Application WO/2016/054338
Kind Code:
A4
Abstract:
Disclosed herein are embodiments of compositions and combinations that can be used in combination with animal food. In some embodiments, the combinations comprise various compositions that can provide health benefits for animals, such as domestic or companion animals and/or feed animals. The combinations can be used to help maintain and/or promote animal health and well-being, and in some embodiments can help promote an increase in animal longevity.

Inventors:
CALABOTTA, David (229 Radio Road, Quincy, IL, 62035, US)
CHAPMAN, James, D. (4880 Brittany Drive, Macon, GA, 31210, US)
COSTIGAN, Tim (229 Radio Road, Quincy, IL, 62305, US)
FORSBERG, Neil, E. (1767 N.W. Kings Blvd, Corvallis, OR, 97330, US)
KNEHANS, Wendell (11726 Summerwood Drive, St. Louis, MO, 63146, US)
MCLEAN, Derek (3318 SW Willamette Avenue, Corvallis, OR, 97333, US)
PUNTENNEY, Steven, B. (1767 N.W. Kings Blvd, Corvallis, OR, 97330, US)
ROWSON, Angela, D. (229 Radio Road, Quincy, IL, 62305, US)
Application Number:
US2015/053439
Publication Date:
April 07, 2016
Filing Date:
October 01, 2015
Export Citation:
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Assignee:
OMNIGEN RESERCH, LLC (1767 N.W. Kings Blvd, Corvallis, OR, 97330, US)
International Classes:
A23K1/16; A23K1/18; A23K1/175; A23K1/14
Attorney, Agent or Firm:
SCHWARTZ, Johanna, P. (Klarquist Sparkman, LLPOne World Trade Center, Suite 1600,121 SW Salmon Stree, Portland OR, 97204, US)
Download PDF:
Claims:
AMENDED CLAIMS

received by the International Bureau on 22 April 2016 (22.04.2016)

We claim:

1. A combination, comprising:

a primary composition comprising (i) about 30-92 wt% mineral clay and (ii) about 1- 40 wt% silica, about 1-30 wt% β-glucan provided by yeast, or a combination thereof; and any one or more of yucca, quillaja, a direct-fed microbial, a vitamin D species, or a plant extract.

2. The combination of claim 1, wherein the primary composition further comprises mannans.

3. The combination of claims 1 or 2, wherein the primary composition further comprises an endoglucanohydrolase.

4. The combination of any one of claims 1-3, wherein the primary composition further comprises about 1-10 wt% mannans.

5. The combination of any one of claims 1-4, wherein the combination comprises each of yucca, quillaja, a direct-fed microbial, a vitamin D species, and a plant extract.

6. The combination of any one of claims 1-5, wherein the combination comprises Quillaja saponaria, Yucca schidigera, B. coagulans, 25-hydroxy vitamin D3, a polyphenol, or any combination thereof.

7. The combination of any one of claims 1-5, wherein the combination comprises Quillaja saponaria, Yucca schidigera, B. coagulans, and 25-hydroxy vitamin D3.

8. The combination of any one of claims 1-7, wherein the combination comprises the composition and any one or more of the yucca, quillaja, direct-fed microbial, vitamin D species, or plant extract are present in a ratio from 1,000: 1 to 1: 1,000 by weight.

9. The combination of any one of claims 1-8, further comprising a metal carbonate, kelp, a niacin supplement, a vitamin B-12 supplement, biotin, d-calcium

63 pantothenate, choline chloride, thiamine mononitrate, pyridoxine hydrochloride, menadione dimethylpyrimidinol bisulfite, riboflavin-5-phosphate, folic acid, soybean oil, calcium aluminosilicate, rice hulls, mineral oil, or any combination thereof.

10. The combination of any one of claims 1-9, wherein the primary composition, is formulated as a powder, a granule, a pellet, a solution, or a suspension.

11. The combination of any one of claims 1-10, wherein the combination is formulated as a powder, a granule, a pellet, a solution, or a suspension.

12. The combination of any one of claims 1-11, further comprising a feedstuff or companion animal food.

13. A combination, comprising:

a primary composition, comprising (i) about 30-92 wt% mineral clay and (ii) about 1- 40 wt% silica, about 1-30 wt% β-glucan provided by yeast, or a combination thereof;

any one or more of Quillaja saponaria, Yucca schidigera, B. coagulans, 25-hydroxy vitamin D3, or a combination thereof; and

a feedstuff or companion animal food.

14. A method, comprising administering to an animal:

(a) a primary composition comprising (i) about 30-92 wt% mineral clay and (ii) about 1-40 wt% silica, about 1-30 wt% β-glucan provided by yeast, or a combination thereof; and

(b) any one or more of yucca, quillaja, a direct-fed microbial, a vitamin D species, or a plant extract.

15. A method, comprising:

selecting a young or geriatric animal;

administering to the animal a combination comprising a primary composition comprising (i) about 30-92 wt% mineral clay and (ii) about 1-40 wt% silica, about 1-30 wt% β-glucan provided by yeast, or a combination thereof, and any one or more of yucca, quillaja, a direct- fed microbial, a vitamin D species, or a plant extract; and

64 wherein administering the combination to the animal promotes an increase in the animal's lifespan relative to an animal that is not administered the combination.

16. The method of claim 14 or 15, wherein the primary composition further comprises mannans, an endoglucanohydrolase, or both.

17. The method of any one of claims 14-16, further comprising administering to the animal a companion animal feed or feedstuff.

18. The method of claim 17, wherein the feedstuff is a feed ration, a mineral supplement, a protein supplement, a premix, molasses, a liquid feed, water, or any combination thereof.

19. The method of claim 17 or 18, wherein the feedstuff or companion animal food is admixed with the combination prior to administration.

20. The method of any one of claims 14-19, wherein the animal is a companion animal.

21. The method of claim 20, wherein the companion animal is a canine or feline.

22. The method of any one of claims 14-19, wherein the animal is a feed animal.

23. The method of claim 22, wherein the feed animal is a domestic fowl or a cow.

24. The method of any one of claims 14-19, wherein the animal is a pig, a fish, a reptile, a crustacean, a rabbit, a sheep, a goat, a deer, a bison, a buffalo, an alpaca, a horse, a donkey, or a llama.

25. The method of any one of claims 14-24, wherein administering the combination to the animal ameliorates at least one deleterious symptom or sign observed or measured in the animal.

65

26. The method of any one of claims 14-25, wherein administering the combination to the animal delays onset of the at least one deleterious symptom or sign observed or measured in the animal.

27. The method of any one of claims 25-26, wherein the at least one deleterious symptom or sign is associated with stiffness, dermatitis, atopy, flea-allergy dermatitis, food allergy dermatitis, contact dermatitis, juvenile dermatitis, osteoarthritis, conjunctivitis/uveitis, pyometra, prostatitis, orchitis cystitis, renal disease, pemphigus vulgaris/foliaceus, lupus, autoimmune hemolytic anemia, rheumatoid arthritis, Addison's Disease, Cushing's disease, hyper and hypothyroidism, diabetes mellitus, diabetes insipidus, inflammatory bowel disease, hemorrhagic gastroenteritis, otitis, distemper virus, parvovirus, coronavirus, herpesvirus, influenza virus, hepatitis virus, salmonellosis, bordetella bronchiseptica, Lyme's disease, leptospirosis, brucellosis, blastomycosis, aspergillosis, cryptococcus, coccidioidomycosis, microsporum/trichophyton, histoplasmosis, coccidiosis, giardiasis, hookworms, roundworms, whipworms, tapeworms, mange, meningitis-arteritis/encelphalitis, acquired myasthenia gravis, lymphosarcoma, osteosarcoma, hemangio sarcoma, mast cell tumor, squamous cell carcinoma, melanoma, leukemia, mammary tumors, lung cancer, testicular cancer, transitional cell carcinoma, brain tumor, laminitis, founder, heart disease, epilepsy, hepatitis, pancreatitis, gingivitis, and combinations thereof.

28. The method of any one of claims 25-27, wherein the at least one deleterious symptom or sign comprises an aberrant immune system biomarker or an aberrant

inflammation biomarker.

29. A combination for promoting an increase in an animal's lifespan or promoting a healthy immune system, comprising:

a primary composition comprising (i) 35-92% mineral clay and (ii) 1-40% silica, about 1-30 wt% β-glucan provided by yeast, or a combination thereof; and

any one or more of yucca, quillaja, a direct-fed microbial, a vitamin D species, or a plant extract in an amount ranging from 5 ppm to 2,000 ppm based on the total dry weight basis of the combination;

wherein the combination causes an increase or decrease in a level of an immune system biomarker or an inflammation biomarker in the animal.

66

30. The combination of claim 29, wherein the increase or decrease ranges from at least 5% to 600%.

31. Use of a combination comprising a primary composition comprising (i) about 30-92 wt% mineral clay and (ii) about 1-40 wt% silica, about 1-30 wt% β-glucan provided by yeast, or a combination thereof; and any one or more of yucca, quillaja, a direct-fed microbial, a vitamin D species, or a plant extract for use in administering to an animal.

32. Use of a combination comprising a primary composition comprising (i) about 30-92 wt% mineral clay and (ii) about 1-40 wt% silica, about 1-30 wt% β-glucan provided by yeast, or a combination thereof, and any one or more of yucca, quillaja, a direct-fed microbial, a vitamin D species, or a plant extract for use in administering to a young or geriatric animal, wherein administering the combination to the animal promotes an increase in the animal's lifespan relative to an animal that is not administered the combination.

33. The use of claim 31 or claim 32, wherein the primary composition further comprises mannans, an endoglucanohydrolase, or both.