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Title:
COMPOSITIONS COMPRISING CINNAMALDEHYDE AND ZINC AND METHODS OF USING SUCH COMPOSITIONS
Document Type and Number:
WIPO Patent Application WO/2016/008642
Kind Code:
A3
Abstract:
Compositions comprise an amount of cinnamaldehyde that is orally tolerable, thus avoiding an unpleasant mouth feeling, and also tolerable in the gastrointestinal tract. The amount of cinnamaldehyde is supplemented by zinc, and the combination is effective to increase at least one of energy expenditure, sympathetic nervous system activity, or fat oxidation, relative to a composition lacking cinnamaldehyde and zinc but otherwise identical. The composition comprising the combination of cinnamaldehyde and zinc can be used in a method to support weight managementor promote weight loss, a method for preventing obesity or overweight, and a method for treating obesity or overweight. In an embodiment, the composition comprising cinnamaldehydeis administered to a human. The composition comprising cinnamaldehydemay be a medicament, a food product or a supplement. The composition can improve one or more of insulin sensitivity, glucose tolerance, cognitive performance, cognition, mood or memory.

Inventors:
MICHLIG GONZALEZ STÉPHANIE (CH)
MEYLAN MERLINI JENNY (CH)
CAMACHO SUSANA (CH)
LE COUTRE JOHANNES (CH)
Application Number:
PCT/EP2015/062696
Publication Date:
March 17, 2016
Filing Date:
June 08, 2015
Export Citation:
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Assignee:
NESTEC SA (CH)
International Classes:
A23L33/00; A23L33/105; A23L33/16; A61K31/11; A61K33/30
Foreign References:
EP1654937A12006-05-10
KR20120122597A2012-11-07
Other References:
C HANDRAMITA BORA: "Effects of Cinnamon on Weight Loss", BUZZLE, 21 November 2012 (2012-11-21), pages 1 - 3, XP055186730, Retrieved from the Internet [retrieved on 20150429]
JOE MARTINO: "Honey & Cinnamon - The Natural Cures & Health Benefits", 23 February 2014 (2014-02-23), pages 1 - 7, XP055186627, Retrieved from the Internet [retrieved on 20150429]
ANONYMOUS: "Water-Based Cinnamon Extract Capsules", GNPD, 1 August 2009 (2009-08-01), pages 1 - 3, XP055235438, Retrieved from the Internet [retrieved on 20151210]
ANONYMOUS: "Instant Cocoa Drink Powder", GNPD, 1 April 2014 (2014-04-01), XP055235458, Retrieved from the Internet [retrieved on 20151210]
ANONYMOUS: "Top Ten Benefits of Zinc | Poliquin Article", 2 September 2012 (2012-09-02), XP055235866, Retrieved from the Internet [retrieved on 20151211]
ADMINISTRATOR: "Health Benefits of Cinnamon", HERBALISM ROOTS- FROM SEEDS TO MEDICINE, 16 May 2014 (2014-05-16), pages 1 - 3, XP055235863, Retrieved from the Internet [retrieved on 20151211]
CHUNG S H ET AL: "5' adenosine monophosphate - activated protein kinase activator for preparing e.g. pharmaceutical composition, to treat and prevent e.g. obesity, comprises cinnamic aldehyde as active ingredient", WPI / THOMSON,, vol. 2012, no. 63, 14 November 2011 (2011-11-14), XP002734719
Attorney, Agent or Firm:
CHAUTARD, Cécile (Avenue Nestlé 55, Vevey, CH)
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