Title:
COMPOSITIONS COMPRISING MILK FAT TRIGLYCERIDES PRODUCED BY MICROBIAL FERMENTATION
Document Type and Number:
WIPO Patent Application WO/2023/168456
Kind Code:
A3
Abstract:
The present disclosure relates to microbial hosts and methods for biosynthesis of compositions comprising milk fat triglycerides. In one aspect, the present disclosure provides engineered host cells (e.g., microbial host cells) for producing triglycerides characteristic of dairy milk by microbial fermentation or bioconversion; the microbial cell expresses a biosynthetic pathway comprising at least one heterologous enzyme, where the biosynthetic pathway produces triglycerides having short chain fatty acids esterified at sn-3. The triglycerides comprises C4, C6, C12 and C18 fatty acids esterified at sn-3.
Inventors:
SHAW ARTHUR (US)
BRUNET YANNICK (US)
KUMARAN AJIKUMAR (US)
SANTOS CHRISTINE (US)
BRUNET YANNICK (US)
KUMARAN AJIKUMAR (US)
SANTOS CHRISTINE (US)
Application Number:
PCT/US2023/063780
Publication Date:
November 16, 2023
Filing Date:
March 06, 2023
Export Citation:
Assignee:
MANUS BIO INC (US)
International Classes:
C12N15/52; A23C9/12; A23C11/04; A23L33/115; C12P7/6463
Domestic Patent References:
| WO2021050759A2 | 2021-03-18 | |||
| WO2021179051A1 | 2021-09-16 |
Foreign References:
| US20130323766A1 | 2013-12-05 |
Attorney, Agent or Firm:
HAYMAN, Mark, L. et al. (US)
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