Title:
COMPOSITIONS, DEVICES, AND METHODS RELATED TO PROSTATE-SPECIFIC MEMBRANE ANTIGEN
Document Type and Number:
WIPO Patent Application WO/2010/135431
Kind Code:
A3
Abstract:
PSMA ligands, compositions, and methods therefore are disclosed where the ligand is a peptide having the sequence X1X2CVEVX3QNSCX4X5 where X1-X5 are independently a natural or non-natural amino acid or a peptide having the sequence CALCEFLG [SEQ ID NO: 1]. Especially preferred aspects include diagnostic reagents for detection and/or quantification of PSMA in a sample, therapeutic reagents, and diagnostic imaging reagents.
Inventors:
WEISS GREGORY A (US)
ARTER JESSICA (US)
DIAZ JUAN E (US)
ARTER JESSICA (US)
DIAZ JUAN E (US)
Application Number:
PCT/US2010/035410
Publication Date:
January 13, 2011
Filing Date:
May 19, 2010
Export Citation:
Assignee:
WEISS GREGORY A (US)
ARTER JESSICA (US)
DIAZ JUAN E (US)
UNIV CALIFORNIA (US)
ARTER JESSICA (US)
DIAZ JUAN E (US)
UNIV CALIFORNIA (US)
International Classes:
C07K4/00; A61K49/00; A61K51/00
Foreign References:
| US20090092965A1 | 2009-04-09 | |||
| US20070020278A1 | 2007-01-25 | |||
| US20080081768A1 | 2008-04-03 |
Other References:
ANDERSSON ET AL: "Pseudogenes, junk DNA, and the dynamics of Rickettsia genomes", MOL. BIOL. EVOL., vol. 18, 2001, pages 829 - 839
MYERS ET AL: "Skewed genomic variability in strains of the toxigenic bacterial pathogen, Clostridium perfringens", GENOME RES., vol. 16, 2006, pages 1031 - 1040, XP002496207, DOI: doi:10.1101/gr.5238106
MATTHIJNSSENS ET AL: "Full genome-based classification of rotaviruses reveals a common origin between human Wa-Like and porcine rotavirus strains and human DS-1-like and bovine rotavirus strains", J. VIROL., vol. 82, 2008, pages 3204 - 3219
DATABASE UNIPROT [online] 3 April 2007 (2007-04-03), WARD B. ET AL, retrieved from http://www.uniprot.org/uniprot/A3JDN2 accession no. EMBL Database accession no. A3JDN2
KANEKO ET AL: "Complete genomic structure of the bloom-forming toxic cyanobacterium Microcystis aeruginosa NIES-843", DNA RES., vol. 14, 2007, pages 247 - 256, XP055200990, DOI: doi:10.1093/dnares/dsm026
MYERS ET AL: "Skewed genomic variability in strains of the toxigenic bacterial pathogen, Clostridium perfringens", GENOME RES., vol. 16, 2006, pages 1031 - 1040, XP002496207, DOI: doi:10.1101/gr.5238106
MATTHIJNSSENS ET AL: "Full genome-based classification of rotaviruses reveals a common origin between human Wa-Like and porcine rotavirus strains and human DS-1-like and bovine rotavirus strains", J. VIROL., vol. 82, 2008, pages 3204 - 3219
DATABASE UNIPROT [online] 3 April 2007 (2007-04-03), WARD B. ET AL, retrieved from http://www.uniprot.org/uniprot/A3JDN2 accession no. EMBL Database accession no. A3JDN2
KANEKO ET AL: "Complete genomic structure of the bloom-forming toxic cyanobacterium Microcystis aeruginosa NIES-843", DNA RES., vol. 14, 2007, pages 247 - 256, XP055200990, DOI: doi:10.1093/dnares/dsm026
Attorney, Agent or Firm:
FESSENMAIER, Martin et al. (Suite 1000Irvine, California, US)
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