COMPOSITIONS FOR LABELING NERVES AND METHODS OF USE

Title:

COMPOSITIONS FOR LABELING NERVES AND METHODS OF USE

Document Type and Number:

WIPO Patent Application WO/2012/031250

Kind Code:

A3

Abstract:

The present invention provides methods for guiding preservation of neurons or nerves during surgery by administering a fluorescently-labeled peptide that associates with (e.g., specifically binds to) the neurons or nerves. The invention further provides targeting molecules of fluorescently-labeled peptides or aptamers that associate with (e.g., specifically bind to) neurons or nerves and for compositions thereof.

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Inventors:

GONZALEZ JESUS (US)
LIU JUNJIE (US)

Application Number:

PCT/US2011/050411

Publication Date:

December 27, 2012

Filing Date:

September 02, 2011

Export Citation:

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Assignee:

AVELAS BIOSCIENCES INC (US)
GONZALEZ JESUS (US)
LIU JUNJIE (US)

International Classes:

C07K7/08; A61K38/08; A61K38/10; A61K47/48; A61K49/14; C07K5/00; C07K7/06

Foreign References:

US20070072251A1	2007-03-29
US7781565B2	2010-08-24
US7452964B2	2008-11-18
US6391280B1	2002-05-21

Other References:

PAN. H. ET AL.: "Lipid membrane editing with peptide cargo linkers in cells and synthetic nanostructures.", THE FASEB JOURNAL., vol. 24, no. 8, August 2010 (2010-08-01), pages 2928 - 37, XP055105455

Attorney, Agent or Firm:

POULOS, Sabrina, D. et al. (650 Page Mill RoadPalo Alto, CA, US)

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