Title:
COMPOSITIONS AND METHODS FOR THE CONVERSION OF SHORT-CHAINED CARBOXYLIC ACIDS TO ALCOHOLS USING CLOSTRIDIAL ENZYMES
Document Type and Number:
WIPO Patent Application WO/2016/164339
Kind Code:
A3
Abstract:
The invention relates to the fields of bacterial metabolism and the utilization or consumption of short-chain carboxylic acids to reduced products. Specifically, it relates to syngas fermentations using monocultures of syngas-utilizing homoacetogenic bacteria for the production of alcohols using native alcohol dehydrogenase.
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Inventors:
REEVES ANDREW (US)
TOBEY RICHARD (US)
ENZIEN MIKE (US)
TOBEY RICHARD (US)
ENZIEN MIKE (US)
Application Number:
PCT/US2016/025991
Publication Date:
December 22, 2016
Filing Date:
April 05, 2016
Export Citation:
Assignee:
SYNATA BIO INC (US)
International Classes:
C12P7/08; C12P7/06; C12P7/16
Foreign References:
| US20110008860A1 | 2011-01-13 | |||
| US20140206052A1 | 2014-07-24 | |||
| US20130102044A1 | 2013-04-25 |
Other References:
PEREZ J M ET AL: "Biocatalytic reduction of short-chain carboxylic acids into their corresponding alcohols with syngas fermentation", BIOTECHNOLOGY AND BIOENGINEERING, WILEY & SONS, HOBOKEN, NJ, US, vol. 110, no. 4, 1 April 2013 (2013-04-01), pages 1066 - 1077, XP002694318, ISSN: 0006-3592, DOI: 10.1002/BIT.24786
ISOM CATHERINE E ET AL: "Improved conversion efficiencies forn-fatty acid reduction to primary alcohols by the solventogenic acetogen "Clostridium ragsdale", JOURNAL OF INDUSTRIAL MICROBIOLOGY AND BIOTECHNOLOGY, BASINGSTOKE, GB, vol. 42, no. 1, 20 November 2014 (2014-11-20), pages 29 - 38, XP035419071, ISSN: 1367-5435, [retrieved on 20141120], DOI: 10.1007/S10295-014-1543-Z
WEIMER PAUL J ET AL: "Production of medium-chain volatile fatty acids by mixed ruminal microorganisms is enhanced by ethanol in co-culture withClostridium kluyveri", BIORESOURCE TECHNOLOGY, vol. 175, 18 October 2014 (2014-10-18), pages 97 - 101, XP029098256, ISSN: 0960-8524, DOI: 10.1016/J.BIORTECH.2014.10.054
ISOM CATHERINE E ET AL: "Improved conversion efficiencies forn-fatty acid reduction to primary alcohols by the solventogenic acetogen "Clostridium ragsdale", JOURNAL OF INDUSTRIAL MICROBIOLOGY AND BIOTECHNOLOGY, BASINGSTOKE, GB, vol. 42, no. 1, 20 November 2014 (2014-11-20), pages 29 - 38, XP035419071, ISSN: 1367-5435, [retrieved on 20141120], DOI: 10.1007/S10295-014-1543-Z
WEIMER PAUL J ET AL: "Production of medium-chain volatile fatty acids by mixed ruminal microorganisms is enhanced by ethanol in co-culture withClostridium kluyveri", BIORESOURCE TECHNOLOGY, vol. 175, 18 October 2014 (2014-10-18), pages 97 - 101, XP029098256, ISSN: 0960-8524, DOI: 10.1016/J.BIORTECH.2014.10.054
Attorney, Agent or Firm:
FENDRICK, Sarah, E. (& Berghoff LLP300 South Wacker Driv, Chicago IL, US)
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