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Title:
COMPOSITIONS AND METHODS FOR THE CONVERSION OF SHORT-CHAINED CARBOXYLIC ACIDS TO ALCOHOLS USING CLOSTRIDIAL ENZYMES
Document Type and Number:
WIPO Patent Application WO/2016/164339
Kind Code:
A3
Abstract:
The invention relates to the fields of bacterial metabolism and the utilization or consumption of short-chain carboxylic acids to reduced products. Specifically, it relates to syngas fermentations using monocultures of syngas-utilizing homoacetogenic bacteria for the production of alcohols using native alcohol dehydrogenase.

Inventors:
REEVES, Andrew (226 North Clinton Street, Unit 316Chicago, IL, 60661, US)
TOBEY, Richard (42W485 Sylvan Lane, St. Charles, IL, 60175, US)
ENZIEN, Mike (6528 Royal Glen Court, Lisle, IL, 60532, US)
Application Number:
US2016/025991
Publication Date:
October 13, 2016
Filing Date:
April 05, 2016
Export Citation:
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Assignee:
SYNATA BIO, INC. (4575 Weaver Parkway, Suite 100Warrenville, IL, 60555, US)
International Classes:
C12P7/08; C12P7/06; C12P7/16
Foreign References:
US20110008860A12011-01-13
US20140206052A12014-07-24
US20130102044A12013-04-25
Other References:
PEREZ J M ET AL: "Biocatalytic reduction of short-chain carboxylic acids into their corresponding alcohols with syngas fermentation", BIOTECHNOLOGY AND BIOENGINEERING, WILEY & SONS, HOBOKEN, NJ, US, vol. 110, no. 4, 1 April 2013 (2013-04-01), pages 1066 - 1077, XP002694318, ISSN: 0006-3592, DOI: 10.1002/BIT.24786
ISOM CATHERINE E ET AL: "Improved conversion efficiencies forn-fatty acid reduction to primary alcohols by the solventogenic acetogen "Clostridium ragsdale", JOURNAL OF INDUSTRIAL MICROBIOLOGY AND BIOTECHNOLOGY, BASINGSTOKE, GB, vol. 42, no. 1, 20 November 2014 (2014-11-20), pages 29 - 38, XP035419071, ISSN: 1367-5435, [retrieved on 20141120], DOI: 10.1007/S10295-014-1543-Z
WEIMER PAUL J ET AL: "Production of medium-chain volatile fatty acids by mixed ruminal microorganisms is enhanced by ethanol in co-culture withClostridium kluyveri", BIORESOURCE TECHNOLOGY, vol. 175, 18 October 2014 (2014-10-18), pages 97 - 101, XP029098256, ISSN: 0960-8524, DOI: 10.1016/J.BIORTECH.2014.10.054
Attorney, Agent or Firm:
FENDRICK, Sarah, E. (McDonnell Boehnen Hulbert, & Berghoff LLP300 South Wacker Driv, Chicago IL, 60606, US)
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