Title:
COMPOSITIONS AND METHODS FOR CONVERTING METHANOL INTO HYDROGEN PEROXIDE AND CARBON DIOXIDE
Document Type and Number:
WIPO Patent Application WO/2021/072146
Kind Code:
A3
Abstract:
The present invention provides for a method for producing hydrogen peroxide comprising: (a) contacting a methanol with methanol oxidase bound with a flavin adenine dinucleotide (FAD) cofactor, such that the methanol is oxidized into a formaldehyde and the FAD cofactor is reduced into FADH2; (b) contacting the formaldehyde with the methanol oxidase or a formate oxidase bound with a FAD cofactor, such that the formaldehyde is oxidized into formate and the FAD is reduced into FADH2; and (c) contacting oxygen with one or more of the FADH2 to produce hydrogen peroxide and oxidize FADH2 into FAD. The present invention also provides for a fusion protein comprising any two or all of methanol oxidase, formate oxidase, and formaldehyde dismutase.
Inventors:
EIBEN CHRISTOPHER B (US)
KEASLING JAY (US)
KEASLING JAY (US)
Application Number:
PCT/US2020/054903
Publication Date:
May 14, 2021
Filing Date:
October 09, 2020
Export Citation:
Assignee:
UNIV CALIFORNIA (US)
International Classes:
C12N15/53; C12N9/04
Foreign References:
| NL2013351A | 2016-05-24 | |||
| DE102013210506A1 | 2014-12-11 | |||
| US20120028333A1 | 2012-02-02 | |||
| US20190233861A1 | 2019-08-01 |
Attorney, Agent or Firm:
OSMAN, Richard, Aron (US)
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