Title:
COMPOSITIONS AND METHODS FOR DIAGNOSING AND TREATING KIDNEY DISORDERS IN A CANINE
Document Type and Number:
WIPO Patent Application WO/2011/079280
Kind Code:
A3
Abstract:
The present invention provides methods for: diagnosing of, devising and monitoring a treatment plan for, and monitoring the status of a kidney disorder characterized by an abnormal loss of renal function, renal failure, reduced glomerular filtration rate or glomerulonephritis, in a canine, wherein the kidney disorder is detectable by utilizing at least one relevant biomarker isolated and measured from a biological test sample taken from such canine. The invention additionally relates to compositions, reagents and kits for carrying out the specified methods.
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Inventors:
AL-MURRANI SAMER (US)
MALLADI SUKHASWAMI (US)
GAO XIANGMING (US)
MALLADI SUKHASWAMI (US)
GAO XIANGMING (US)
Application Number:
PCT/US2010/062031
Publication Date:
November 17, 2011
Filing Date:
December 23, 2010
Export Citation:
Assignee:
HILLS PET NUTRITION INC (US)
AL-MURRANI SAMER (US)
MALLADI SUKHASWAMI (US)
GAO XIANGMING (US)
AL-MURRANI SAMER (US)
MALLADI SUKHASWAMI (US)
GAO XIANGMING (US)
International Classes:
G01N33/68
Foreign References:
| EP1808694A1 | 2007-07-18 |
Other References:
FORTERRE S ET AL: "PROTEIN PROFILING OF URINE FROM DOGS WITH RENAL DISEASE USING PROTEINCHIP ANALYSIS", JOURNAL OF VETERINARY DIAGNOSTIC INVESTIGATION, AAVLD, COLUMBIA, MO, US, vol. 16, no. 4, 1 July 2004 (2004-07-01), pages 271 - 277, XP008068536, ISSN: 1040-6387
SCHMIDT M K ET AL: "Effect of azotemia on serum N-terminal proBNP concentration in dogs with normal cardiac function: a pilot study.", JOURNAL OF VETERINARY CARDIOLOGY : THE OFFICIAL JOURNAL OF THE EUROPEAN SOCIETY OF VETERINARY CARDIOLOGY MAY 2009 LNKD- PUBMED:19394913, vol. 11 Suppl 1, May 2009 (2009-05-01), pages S81 - S86, XP002636356, ISSN: 1875-0834
MIYAGAWA YUICHI ET AL: "Evaluation of the measurement of serum cystatin C by an enzyme-linked immunosorbent assay for humans as a marker of the glomerular filtration rate in dogs.", THE JOURNAL OF VETERINARY MEDICAL SCIENCE / THE JAPANESE SOCIETY OF VETERINARY SCIENCE SEP 2009 LNKD- PUBMED:19801896, vol. 71, no. 9, September 2009 (2009-09-01), pages 1169 - 1176, XP002636357, ISSN: 0916-7250
BRAUN J -P ET AL: "Plasma cystatin C in the dog: Reference values and variations with renal failure", COMPARATIVE CLINICAL PATHOLOGY 200201 GB LNKD- DOI:10.1007/S580-002-8081-2, vol. 11, no. 1, January 2002 (2002-01-01), pages 44 - 49, XP002636429, ISSN: 1618-5641
JIA-LIN LEE ET AL: "Secreted Frizzled Related Protein 2 (sFRP2) Decreases Susceptibility to UV-Induced Apoptosis in Primary Culture of Canine Mammary Gland Tumors by NF-[kappa]B Activation or JNK Suppression", BREAST CANCER RESEARCH AND TREATMENT, KLUWER ACADEMIC PUBLISHERS, BO, vol. 100, no. 1, 22 June 2006 (2006-06-22), pages 49 - 58, XP019433510, ISSN: 1573-7217, DOI: DOI:10.1007/S10549-006-9233-9
SCHMIDT M K ET AL: "Effect of azotemia on serum N-terminal proBNP concentration in dogs with normal cardiac function: a pilot study.", JOURNAL OF VETERINARY CARDIOLOGY : THE OFFICIAL JOURNAL OF THE EUROPEAN SOCIETY OF VETERINARY CARDIOLOGY MAY 2009 LNKD- PUBMED:19394913, vol. 11 Suppl 1, May 2009 (2009-05-01), pages S81 - S86, XP002636356, ISSN: 1875-0834
MIYAGAWA YUICHI ET AL: "Evaluation of the measurement of serum cystatin C by an enzyme-linked immunosorbent assay for humans as a marker of the glomerular filtration rate in dogs.", THE JOURNAL OF VETERINARY MEDICAL SCIENCE / THE JAPANESE SOCIETY OF VETERINARY SCIENCE SEP 2009 LNKD- PUBMED:19801896, vol. 71, no. 9, September 2009 (2009-09-01), pages 1169 - 1176, XP002636357, ISSN: 0916-7250
BRAUN J -P ET AL: "Plasma cystatin C in the dog: Reference values and variations with renal failure", COMPARATIVE CLINICAL PATHOLOGY 200201 GB LNKD- DOI:10.1007/S580-002-8081-2, vol. 11, no. 1, January 2002 (2002-01-01), pages 44 - 49, XP002636429, ISSN: 1618-5641
JIA-LIN LEE ET AL: "Secreted Frizzled Related Protein 2 (sFRP2) Decreases Susceptibility to UV-Induced Apoptosis in Primary Culture of Canine Mammary Gland Tumors by NF-[kappa]B Activation or JNK Suppression", BREAST CANCER RESEARCH AND TREATMENT, KLUWER ACADEMIC PUBLISHERS, BO, vol. 100, no. 1, 22 June 2006 (2006-06-22), pages 49 - 58, XP019433510, ISSN: 1573-7217, DOI: DOI:10.1007/S10549-006-9233-9
Attorney, Agent or Firm:
MCGARRAH, Shannon (909 River RoadPiscataway, NJ, US)
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