Title:
COMPOSITIONS AND METHODS FOR ENHANCING ONCOLYTIC VIRUS EFFICACY
Document Type and Number:
WIPO Patent Application WO/2016/119052
Kind Code:
A8
Abstract:
Provided are compounds that enhance the efficacy of viruses by increasing spread of the virus in cells, increasing the titer of virus in cells, or increasing the cytotoxicity of virus to cells. Other uses, compositions and methods of using same are also provided.
Inventors:
DIALLO JEAN-SIMON (CA)
BODDY CHRISTOPHER NOYCE (CA)
DORNAN MARK (CA)
KRISHNAN RAMYA (CA)
LE BOEUF FABRICE (CA)
BELL JOHN C (CA)
MACKLIN ANDREW (CA)
SMITH JEFFREY (CA)
BODDY CHRISTOPHER NOYCE (CA)
DORNAN MARK (CA)
KRISHNAN RAMYA (CA)
LE BOEUF FABRICE (CA)
BELL JOHN C (CA)
MACKLIN ANDREW (CA)
SMITH JEFFREY (CA)
Application Number:
PCT/CA2016/050062
Publication Date:
September 01, 2016
Filing Date:
January 26, 2016
Export Citation:
Assignee:
OTTAWA HOSPITAL RES INST (CA)
UNIV OTTAWA (CA)
UNIV OTTAWA (CA)
International Classes:
A61K31/4015; A61K31/341; A61K31/36; A61K31/365; A61K31/4025; A61K31/404; A61K31/4192; A61K31/422; A61K31/4439; A61K31/4745; A61K31/50; A61K35/00; A61K35/76; C07D207/38; C07D207/40; C07D237/14; C07D307/60; C07D307/66
Attorney, Agent or Firm:
SCHROEDER, Hans et al. (160 Elgin Street Suite 260, Ottawa Ontario K1P 1C3, CA)
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