COMPOSITIONS AND METHODS FOR GENOTYPING CES1 GENETIC VARIANTS AND USE THEREOF

Title:

COMPOSITIONS AND METHODS FOR GENOTYPING CES1 GENETIC VARIANTS AND USE THEREOF

Document Type and Number:

WIPO Patent Application WO/2012/145514

Kind Code:

A3

Abstract:

The invention features compositions and methods that are useful for genotyping CESl isoforms (CESlAl, CES1A2, CES1A3). The ability to specifically genotype one or more CESl isoforms (e.g. CESlAl) is useful for assessing drug metabolism in a subject and guiding treatment selection.

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Inventors:

MARKOWITZ JOHN SETH (US)
ZHU HAOJIE (US)

Application Number:

PCT/US2012/034255

Publication Date:

February 28, 2013

Filing Date:

April 19, 2012

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Assignee:

UNIV FLORIDA (US)
MARKOWITZ JOHN SETH (US)
ZHU HAOJIE (US)

International Classes:

C12Q1/68; C12N9/16; C12N15/55

Foreign References:

US20110020801A1	2011-01-27
US20020076786A1	2002-06-20
US20070184457A1	2007-08-09

Attorney, Agent or Firm:

CORLESS, Peter, F. et al. (P.O. BOX 55874Boston, MA, US)

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