Title:
COMPOSITIONS AND METHODS FOR IDENTIFYING MODULATORS OF HAUSP
Document Type and Number:
WIPO Patent Application WO2006072048
Kind Code:
B1
Abstract:
The disclosure relates to compositions and methods for modulating the biological activity of HAUSP protein. Among the activities that can be modulated are binding of HAUSP protein with proteins such as p53, MDM2, and EBNA1; modulation of HAUSP isopeptidase activity; and modulation of binding of HAUSP protein with ubiquitin and ubiquitinated proteins.
Inventors:
SHI YIGONG (US)
Application Number:
PCT/US2005/047572
Publication Date:
March 01, 2007
Filing Date:
December 30, 2005
Export Citation:
Assignee:
UNIV PRINCETON (US)
SHI YIGONG (US)
SHI YIGONG (US)
International Classes:
A61K38/04; C07K5/00; C07K7/00; C07K16/00; C07K17/00
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