Title:
COMPOSITIONS AND METHODS FOR IMPROVING VIRAL TRANSDUCTION
Document Type and Number:
WIPO Patent Application WO/2024/015853
Kind Code:
A3
Abstract:
Disclosed herein are fusion proteins comprising the CR3 domain of the low density lipoprotein (LDLR) and a polypeptide with phase behavior. Also provided herein are polypeptides with phase behavior. Additionally provided herein are methods of improving or decreasing viral transduction efficiency comprising administering a fusion protein or polypeptide with phase behavior described herein.
Inventors:
VOTAW NICOLE (US)
DZURICKY MICHAEL (US)
LUGINBUHL KELLI M (US)
DZURICKY MICHAEL (US)
LUGINBUHL KELLI M (US)
Application Number:
PCT/US2023/070044
Publication Date:
April 18, 2024
Filing Date:
July 12, 2023
Export Citation:
Assignee:
DONALDSON CO INC (US)
International Classes:
C07K14/00; A61K38/00; A61K39/00; C07K1/00; C07K14/47; C12N15/00; C12P21/06
Attorney, Agent or Firm:
MAGNOTTI, Elizabeth L. et al. (US)
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