Title:
COMPOSITIONS AND METHODS FOR MODULATING LIPID AND STEROID METABOLISM
Document Type and Number:
WIPO Patent Application WO/2020/185581
Kind Code:
A3
Abstract:
Provided herein are methods and compositions related to promoting or reducing colonization of spore-forming bacteria in a patient's gut, comprising administering a serotonin receptor agonist or a selective serotonin reuptake inhibitor, respectively. In some aspects, provided herein are methods of modulating lipid and steroid metabolism.
Inventors:
HSIAO ELAINE (US)
FUNG THOMAS (US)
FUNG THOMAS (US)
Application Number:
PCT/US2020/021434
Publication Date:
December 16, 2021
Filing Date:
March 06, 2020
Export Citation:
Assignee:
UNIV CALIFORNIA (US)
International Classes:
A61K31/405; A61K31/138; A61K35/742; A61K45/06; A61P1/00; A61P1/14; A61P1/16; A61P3/06; C12N1/00; C12R1/01
Domestic Patent References:
| WO2016036615A1 | 2016-03-10 | |||
| WO2017136795A1 | 2017-08-10 | |||
| WO2018042304A1 | 2018-03-08 | |||
| WO2016011019A1 | 2016-01-21 |
Other References:
GERSHON, M.D. TACK, J.: "The Serotonin Signaling System: From Basic Understanding To Drug Development for Functional GI Disorders", GASTROENTEROLOGY, ELSEVIER INC., US, vol. 132, no. 1, 20 January 2007 (2007-01-20), US , pages 397 - 414, XP005920691, ISSN: 0016-5085, DOI: 10.1053/j.gastro.2006.11.002
Attorney, Agent or Firm:
HALSTEAD, David, P. et al. (US)
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