Title:
COMPOSITIONS AND METHODS FOR SELECTIVELY BINDING AMINES OR AMINO ACID ENANTIOMERS OVER THEIR COUNTER-ENANTIOMERS
Document Type and Number:
WIPO Patent Application WO2001068729
Kind Code:
A8
Abstract:
Naphthyl crown ether ligand molecules containing at least two naphthyl groups that are covalently bonded to suitable solid supports and coated by hydrophobic organic solvents are disclosed. These compositions and associated methods are characterized by selectivity of desired amine or amino acid enantiomers over their counter-enantiomers and derivatives. The composition preferably has an alpha -value greater than or equal to 4. This allows for the separation of such enantiomers with nonchromatographic resin bed separations of three separation stages or less.
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Inventors:
BRUENING RONALD L
KRAKOWIAK KRZYSZTOF E
KRAKOWIAK KRZYSZTOF E
Application Number:
PCT/US2001/007550
Publication Date:
March 21, 2002
Filing Date:
March 09, 2001
Export Citation:
Assignee:
IBC ADVANCED TECH INC (US)
International Classes:
B01J20/26; B01J20/281; B01J20/283; G01N30/00; B01J20/284; B01J20/285; B01J20/291; B01J20/34; B01J45/00; B01J47/02; C07B57/00; C07C227/34; C07C229/08; C07D323/00; G01N30/26; G01N30/88; (IPC1-7): C08F112/08; C08F112/14; C07D323/00
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