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Title:
COMPOSITIONS AND METHODS FOR TREATING ANEMIA
Document Type and Number:
WIPO Patent Application WO/2014/200773
Kind Code:
A3
Abstract:
Provided herein are specific doses of, and dosing regimens for, using a HIF prolyl hydroxylase inhibitor in treating or preventing anemia, such as anemia secondary to or associated with chronic kidney disease, anemia associated with or resulting from chemotherapy, or anemia associated with AIDS.

Inventors:
SHALWITZ ROBERT (US)
HARTMAN CHARLOTTE (US)
BUCH AKSHAY (US)
SHALWITZ ISAIAH (US)
JANUSZ JOHN (US)
GARDNER JOSEPH (US)
Application Number:
PCT/US2014/040889
Publication Date:
March 05, 2015
Filing Date:
June 04, 2014
Export Citation:
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Assignee:
AKEBIA THERAPEUTICS INC (US)
International Classes:
A61K31/4439; A01N43/40; A61K31/345
Foreign References:
US20070299086A12007-12-27
US20120309977A12012-12-06
US20140057892A12014-02-27
Other References:
"CLINICALTRIALS.GOV: ARCHIVE: NCT01235936 Nn 2012_09_30", 30 August 2012 (2012-08-30), pages 1 - 3, XP055328354, Retrieved from the Internet
"AKEBIA CLOSES $41 MILLION SERIES C", 4 June 2013 (2013-06-04), pages 1 - 2, XP026740630, Retrieved from the Internet
STOHLAWETZ, PJ ET AL.: "Effects Of Erythropoietin On Platelet Reactivity And Thrombopoiesis In Humans.", BLOOD., vol. 95, no. 9, 2000, pages 2983 - 2989, XP002481264
PASQUALETTI, P ET AL.: "Circadian Rhythm Of Serum Erythropoietin In Myelodysplastic Syndromes.", EUROPEAN REVIEW FOR MEDICAL AND PHARMACOLOGICAL SCIENCES., vol. 4, 2000, pages 111 - 115, XP055303710
Attorney, Agent or Firm:
MARTINEK, Sebastian, A. et al. (222 East 41 St StreetNew York, NY, US)
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