Title:
COMPOSITIONS AND METHODS FOR TREATING BIOFILMS
Document Type and Number:
WIPO Patent Application WO/2016/205902
Kind Code:
A8
Abstract:
The present invention relates to a novel composition for use in inhibiting or treating microbial biofilm formation, said composition comprising a plant defensin or a peptide derivative thereof and an antifungal compound, preferably caspofungin, anidulafungin, micafungin, or amphotericin B. Accordingly, the present invention relates to use of said composition for the inhibition or treatment of biofilms, particularly fungal biofilms, such as Candida biofilms, in a subject or on a surface or other medium susceptible to biofilm formation.
Inventors:
CAMMUE BRUNO (BE)
COOLS TANNE (BE)
DRIJFHOUT JAN WOUTER (NL)
THEVISSEN KARIN (BE)
COOLS TANNE (BE)
DRIJFHOUT JAN WOUTER (NL)
THEVISSEN KARIN (BE)
Application Number:
PCT/BE2016/000028
Publication Date:
March 30, 2017
Filing Date:
June 23, 2016
Export Citation:
Assignee:
KATHOLIEKE UNIV LEUVEN KU LEUVEN RES & DEV (BE)
ACADEMISCH ZIEKENHUIS LEIDEN (NL)
ACADEMISCH ZIEKENHUIS LEIDEN (NL)
International Classes:
A61K38/02; A61K38/10; C07K2/00; C07K7/00
Attorney, Agent or Firm:
KATHOLIEKE UNIVERSITEIT LEUVEN KU LEUVEN RESEARCH & DEVELOPMENT (BE)
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