Title:
COMPOSITIONS AND METHODS FOR TREATING DISEASES
Document Type and Number:
WIPO Patent Application WO2005084301
Kind Code:
A3
Abstract:
This invention relates to compositions and methods for treatment of vascular conditions. The invention provides arginine polymers and arginine homopolymers for the treatment and/or prevention of glaucoma, pulmonary hypertension, asthma, chronic obstructive pulmonary disease, erectile dysfunction, Raynaud's syndrome, heparin overdose, vulvodynia, and would healing. The invention also provides arginine polymers and arginine homopolymers for use in organ perfusate and preservation solutions.
Inventors:
ROTHBARD JONATHAN B (US)
MCGRANE PAUL L (US)
ENGLEMAN EDGAR G (US)
FATHMAN C GARRISON (US)
KREIDER ERIK (US)
MCGRANE PAUL L (US)
ENGLEMAN EDGAR G (US)
FATHMAN C GARRISON (US)
KREIDER ERIK (US)
Application Number:
PCT/US2005/006567
Publication Date:
September 14, 2006
Filing Date:
March 01, 2005
Export Citation:
Assignee:
LUMEN THERAPEUTICS LLC (US)
ROTHBARD JONATHAN B (US)
MCGRANE PAUL L (US)
ENGLEMAN EDGAR G (US)
FATHMAN C GARRISON (US)
KREIDER ERIK (US)
ROTHBARD JONATHAN B (US)
MCGRANE PAUL L (US)
ENGLEMAN EDGAR G (US)
FATHMAN C GARRISON (US)
KREIDER ERIK (US)
International Classes:
A61K38/04; A61K31/137; A61K38/08; A61K31/4178; A61K31/5377; A61K38/00
Domestic Patent References:
| WO2003072039A2 | 2003-09-04 |
Other References:
SAYERS R.D.: "Aortic aneurysms, inflammatory pathways and nitric oxide", ANN. R. COLL. SURG. ENGL., vol. 84, 2002, pages 239 - 246, XP003000243
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