Title:
COMPOSITIONS AND METHODS FOR THE TREATMENT OF CHRONIC DISEASES AND INFLAMMATORY DISORDERS
Document Type and Number:
WIPO Patent Application WO/2013/168013
Kind Code:
A3
Abstract:
The invention relates to the compounds of formula (I) or its pharmaceutical acceptable salts, as well as polymorphs, solvates, enantiomers, stereoisomers and hydrates thereof. The pharmaceutical compositions comprising an effective amount of compounds of formula (I), and methods for the treatment of chronic diseases and inflammatory disorders may be formulated for oral, buccal, rectal, topical, transdermal, transmucosal, intravenous, parenteral administration, syrup, or injection. Such compositions may be used to treatment of intermittent claudication, obstructed arteries in the limbs, vascular dementia, Peyronie's disease, neuropathic injuries, sickle cell disease, nausea and headaches in the mountains (altitude sickness), acute alcoholic and non-alcoholic steatohepatitis, alcoholic liver disease, fibrotic lesions induced by radiation therapy for cancer, cytokine release syndrome, endometriosis, venous disease, inflammation, cancer, stroke, thrombosis, sepsis, gangrene, infection, type 1 diabetes, type 2 diabetes, pancreatic beta cell degeneration, beta cell dysfunction, respiratory diseases, rheumatoid arthritis, arthritis, osteoarthritis and vascular disease.
Inventors:
KANDULA MAHESH (IN)
Application Number:
PCT/IB2013/051552
Publication Date:
September 01, 2016
Filing Date:
February 27, 2013
Export Citation:
Assignee:
CELLIX BIO PRIVATE LTD (IN)
International Classes:
A61K31/522; C07D473/04; A61P3/10; A61P7/02; A61P9/10; A61P11/00; A61P19/02
Foreign References:
| US20110077255A1 | 2011-03-31 | |||
| US4636507A | 1987-01-13 |
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