Title:
COMPOSITIONS AND METHODS FOR TREATMENT AND DETECTION OF CANCERS
Document Type and Number:
WIPO Patent Application WO/2016/123591
Kind Code:
A3
Abstract:
Pharmaceutical composition comprising antibodies or antigen binding fragments thereof that bind to globo H, SSEA3, and SSEA-4 are disclosed herein, as well as methods of use thereof. Methods of use include, without limitation, cancer therapies and diagnostics. The antibodies of the disclosure can bind to certain cancer cell surfaces. Exemplary targets of the antibodies disclosed herein can include carcinomas, such as those in brain, skin, bone, lungs, breast, esophagus, stomach, liver, bile duct, pancreas, colon, kidney, cervical, ovarian, and/or prostate cancer.
Inventors:
WONG CHI-HUEY (US)
HSU TSUI-LING (TW)
LOU YI-WEI (TW)
LIN CHIH-WEI (TW)
YEH SHIH-CHI (TW)
WU CHUNG-YI (TW)
WU HAN-CHUNG (TW)
HSU TSUI-LING (TW)
LOU YI-WEI (TW)
LIN CHIH-WEI (TW)
YEH SHIH-CHI (TW)
WU CHUNG-YI (TW)
WU HAN-CHUNG (TW)
Application Number:
PCT/US2016/015856
Publication Date:
December 15, 2016
Filing Date:
January 30, 2016
Export Citation:
Assignee:
ACADEMIA SINICA
WONG CHI-HUEY (US)
WONG CHI-HUEY (US)
International Classes:
A61K39/395; C07K16/00; C07K16/28; C12N5/07; G01N33/53
Domestic Patent References:
| WO2004063351A2 | 2004-07-29 |
Foreign References:
| US20100047827A1 | 2010-02-25 | |||
| US20140178365A1 | 2014-06-26 | |||
| US20100136009A1 | 2010-06-03 | |||
| US20130189258A1 | 2013-07-25 | |||
| US20100022026A1 | 2010-01-28 |
Attorney, Agent or Firm:
NORTON, Vicki, G. (750 B StreetSuite 290, San Diego CA, US)
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