Login| Sign Up| Help| Contact|

Patent Searching and Data


Title:
COMPOSITIONS FOR TREATMENT AND PREVENTION OF DIABETIC COMPLICATIONS USING OSTEOMELES SCHWERINAE
Document Type and Number:
WIPO Patent Application WO/2011/055869
Kind Code:
A1
Abstract:
The present invention relates to a therapeutic agent for diabetic complications and a treatment method for diabetic complications using the same, and more specifically, to an agent for prevention and treatment of diabetic complications containing extracts and fractions of Osteomeles schwerinae as active ingredients, wherein the extracts and fractions of Osteomeles schwerinae are confirmed to prevent the generation of advanced glycation endproducts, which is an indicator of diabetic complications, and the activation of aldose reductase, and to have an anti-cataract effect and anti-oxidative activity.

Inventors:
KIM JIN SOOK (KR)
JANG DAE SIK (KR)
KIM YOUNG SOOK (KR)
LEE YUN MI (KR)
KIM JOO-HWAN (KR)
SHON EUNJIN (KR)
KIM JUNGHYUN (KR)
KIM CHAN-SIK (KR)
KIM OHN SOON (KR)
JUNG DONG HO (KR)
KIM NAN HEE (KR)
YOO NAM-HEE (KR)
LEE JUN (KR)
Application Number:
PCT/KR2009/006491
Publication Date:
May 12, 2011
Filing Date:
November 05, 2009
Export Citation:
Click for automatic bibliography generation   Help
Assignee:
KOREA INST ORIENTAL MEDICINE (KR)
KIM JIN SOOK (KR)
JANG DAE SIK (KR)
KIM YOUNG SOOK (KR)
LEE YUN MI (KR)
KIM JOO-HWAN (KR)
SHON EUNJIN (KR)
KIM JUNGHYUN (KR)
KIM CHAN-SIK (KR)
KIM OHN SOON (KR)
JUNG DONG HO (KR)
KIM NAN HEE (KR)
YOO NAM-HEE (KR)
LEE JUN (KR)
International Classes:
A61K36/73; A23L1/30; A61P13/12; A61P35/00; A61P39/06
Foreign References:
JPH069326A1994-01-18
EP0117600A11984-09-05
Other References:
BIOCHEM J., vol. 58, no. 1, 1954, pages 122 - 125, XP008149290
BIOCHEMICAL SYSTEMATICS AND ECOLOGY, vol. 31, 2003, pages 99 - 101, XP008149291
VINSON, J. A. ET AL., J. NUTRITIONAL BIOCHEMISTRY, vol. 7, 1996, pages 559 - 663
SMITH, P. R. ET AL., EUR. J. BIOCHEM., vol. 210, 1992, pages 729 - 739
BROWNLEE, M. ET AL., SCIENCES, vol. 232, 1986, pages 1629 - 1632
YOKOZAWA, T. ET AL., J. OF TRAD. MED., vol. 18, 2001, pages 107 - 112
KIM ET AL.: "Diabetes", KOREA MEDICAL BOOK PUBLISHER, pages: 483
SOULIS-LIPAROTA, T. ET AL., DIABETOLOGIA, vol. 38, 1995, pages 357 - 394
NAKAMURA, N. ET AL., FREE RADIC BIOL. MED., vol. 29, 2000, pages 17 - 25
BROWNLEE, M. ET AL., N. ENGL. MED., vol. 318, 1988, pages 1315 - 1321
EDELSTEIN, D. ET AL., DIABETES, vol. 41, 1992, pages 26 - 29
ZHONG HUA BEN CAO, SHANGHAI KEXUE JISHU CHUBANSH, vol. 4, pages 2677
TOKUDA H. ET AL.: "Book of Abstract of 53rd GA Congress joint with SIF", 2005, pages: 076
VINSON, J.A. ET AL., J. NUTR. BIOCHEM., vol. 7, 1996, pages 659 - 663
ENGVALL, E. ET AL., J IMMUNOCHEM., vol. 8, 1971, pages 871 - 874
BRAND-WILLIAMS W ET AL., TECHNOLOGY, vol. 28, 1995, pages 25 - 30
SPECTOR ET AL., EXP. EYE RESEARCH, vol. 57, 1993, pages 656 - 667
BRADFORD, M., ANALYTICAL BIOCHEMISTRY, vol. 72, 1976, pages 248 - 254
OBAZAWA H. ET AL., INVEST. OPTHALMOL, vol. 13, 1974, pages 204
CHAND ET AL., EXP. EYE RESEARCH, vol. 35, 1982, pages 491 - 497
Attorney, Agent or Firm:
LEE, WON-HEE (KR)
이원희 (KR)
Download PDF: